423 resultaten
The main hypothesis is that use of Oncokompas will be superior to care as usual to reduce caregiver burden and to improve self-efficacy and quality of life, and it is expected that Oncokompas will improve quality-adjusted life years (QALYs) at…
We hypothesize that increased disease activity (i.e. more inflammation) is associated with an increased risk of developing ID.
The objective is to investigate whether application of a stepwise work-up strategy in primary care patients with uncontrolled hypertension results in better blood pressure control in a cost-effective manner.
The hypothesis of this study is that a difference in mental well-being can be observed after insertion of an LNG-IUD compared to Cu-IUD insertion.
1) Online treatment for nightmares is more effective than a wait-list control group. 2) Efficacy of online treatment is mediated by 'nightmare mastery'
We expect that the intervention group, in which employees diagnosed with cancer inform their employer about an online toolbox, return to work more often, provided with a higher degree of successfulness, compared with the control group, in which…
Nowadays, the hysteroscopic morcellator (HM) is a widely used technique for removal of intrauterine polyps. Various mechanical, motor-driven tissue removal systems are used in clinical setting (Truclear; Medtronic, Minneapolis Minnesota, MyoSure;…
Ischemia driven (FFR) complete percutaneous revascularisation of all significant stenosis in the non-culprit lesion performed within the index PCI procedure will improve clinical outcomes compared to the usual care, guided by discretion of the…
Kidney transplantation is the only treatment offering long-term benefit to patients with chronic kidney failure. Urological complications after kidney transplantation, such as urinary leakage and ureteral strictures, are associated with significant…
End stage kidney disease (ESKD) ranks among the most severe chronic non-communicable diseases with an unmet medical need, given the high (between 10% and 20%) and stable annual mortality rates in ESKD patients treated with dialysis. Kidney…
Multiple sclerosis (MS) is a brain disease, in which myelin sheaths in the brain and spinal cord are damaged. If repair of myelin damage is incomplete, nerve terminals will be irreversibly destroyed, leading to neurological symptoms. Ineffective…
Induction of labour in midwife led care leads to similar effectiveness overall, similar maternal en neonatal outcomes and an increase in patient satisfaction compared to amniotomy in secondary care.
human milk will phase separate and thereby empty differently from infant formula
Following the implementation we expect an increase in number of patients receiving pain medication, an increase in analgesic dosages, decrease of PAIC scores. With regard to the process evaluation we expect good interrater reliability and a…
Patients benefit from shared decision making and this results in a well chosen treatment decision.
We expect that psychosomatic therapy for patients frequently attending primary care with medically unexplained symptoms improves daily functioning, decreases severity of the complaints symptoms and the care consumption, while lowering costs.
We hypothesize that esophageal screening with Lugol chromoendoscopy, in all patients with oro- and hypopharyngeal head and neck squamous cell carcinoma or alcohol abuse, will result in an increased detection rate of esophageal second primary tumors…
Children in the intervention group will consume (a) more water and (b) less sugar sweetened beverages after the intervention compared to the control group.
A single subanesthetic dose of intranasal ketamine is able to diminisch acute suicidal ideation and behaviour, regardless of the underlying diagnosis.
Fecal Microbiota transplantation, applied through a nasoduodenal tube will eliminate intestinal carriage of VRE after a six month follow up period.