3309 resultaten
Flow cytometric analysis of circulating melanoma cells after enrichment by leukapheresis: FAME study
We hypothesize that presence of CMCs could be a potential prognostic biomarker in patients with melanoma, in particular for patients with stage III melanoma. Given the low numbers of CTCs in this latter setting, we therefore aim to optimize a…
The smartphone connected MED as AAF is a valid screening instrument for application in transmural care in the Netherlands.
Oral fosfomycin might be an effective antibiotic to treat men with febrile urinary tract infection caused by E. coli
By providing patients reliable information and daily checklists via an app, we aim to give the patient a tool to be involved in the management of the catheter use. In this way, inappropriate use should be better signaled and discouraged, and the…
1. A frequency of two sessions per week is more effective than a frequency of one session per week. 2. Treatment type (EMDR vs.) ImRs moderates the frequency effect. 3. The frequency effect is mediated by memory, relationships and motivational…
Sentinel node navigation surgery in early esophageal adenocarcinoma is feasible and safe.
The hypothesis formulation for the primary outcome parameter is: - H0: The effect of using product A is unequal to the effect of using product B with respect to serum P AUC0-360 [mmol/L*min] in subjects with elevated gastric pH. - H1: The effect of…
In this study we hope to provide early detection of a treatable cause of pancreatitis by endoscopic ultrasound, and we hope to prevent unnecessary exposure to the rare but serious complications of cholecystectomy. This way, we will be able to…
We hypothesize that DM1 is accompanied by impairments in whole-body and/or muscle metabolism.
We hypothesize that induction of trained immunity through BCG vaccination may improve host defence mechanisms of patients throughout the perioperative period.
SJC rehabilitation programme significantly improves daily function and pain in chronic, therapy resistent pelvic, back and neckpain patients
The diagnostic and therapeutic yield of TTE in this patient group can be improved by selection of patients resulting in a decrease in number of unnecessary TTEs and cost of care.
4 weeks of consumption of an infant formula containing milk fat reduces calcium soap formation compared to the reference formula.
The investigators of this research project are hypothesizing that the South of Limburg, the Netherlands, may be facing an epidemic of infectious endocarditis (IE) during the last 10 to 15 years. Several factors might contribute to this phenomenon:…
We hypothesize that the Visual Analogue Scale (VAS) for dyspnea can detect EIB (exercise-induced bronchoconstriction), and thus uncontrolled asthma, in asthmatic children. Furthermore we hypothesize that combining the VAS for dyspnea with the (C-)…
H0: There is no statistically significant difference between a Cobb angle, measured in supine position compared to a Cobb angle measured in standing position in geriatric outpatients.
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• To determine between-subject and within-subject variability of the study endpoints. • To determine the differences between subjects and healthy controls regarding the study endpoints. • To identify suitable endpoints for future clinical trials in…
• To determine if buprenorphine action at the MOR receptor can inhibit the respiratory depression response to IV fentanyl injection in healthy subjects and patients with chronic opioid use; • To determine if therapeutic concentrations achieved with…
Addition of Partner for Change Outcome Management System (PCOMS) to individual treatment will result in a significant decrease of drop-out compared to individual treatment without PCOMS in a forensic outpatient clinic in the Netherlands. A sub-…