3400 resultaten
Primair wordt het effect van 2 verschillende behandelrichtlijnen vitamine D suppletie met verschillende onderhoudsdoseringen op de 25(OH)D3 concentratie na 12 maanden onderzocht. Daarnaast wordt er gekeken of er verbeteringen zijn op de functionele…
Het vergelijken van de standaardbehandeling met intravesicale chemotherapie (Mitomycine C) met intravesicale chemotherapie (met Mitomycine C) in combinatie met locoregionale 70 MHz hyperthermie bij patiënten met een intermediate risico niet-…
OBJECTIVE: To evaluate the immediate and longer-term effects of early cognitive rehabilitation on cognitive performance and self-reported symptoms/functioning in patients with low-grade gliomas and meningiomas, in a prospective randomized trial.…
The main aim of this study is to test the effectiveness of the intervention ‘Take it personal!’ in decreasing substance use by adolescents (age 14 – 21 years old) with mild to borderline ID en behavioral problems who are admitted to treatment…
In this explorative study we will examine the impact of daily ischemic preconditioning on brachial artery endothelial function (measured as FMD%, before and after IRI) during 7 days in the non-shunt arm and lower limb in patients with end-stage…
Het doel van het onderzoek is om het gebruiksgemak van en ervaringen met PatientCoach te evalueren in eenimplementatiestudie bij patiënten met chronische obstructieve klachten (astma en COPD), hypertensie enDiabetes Mellitus.Vraagstellingen- In…
Different studies have shown that a hunter-gatherer type diet is effective in improving glucose regulation and lipid profile. I want to investigate if the hypothese that this type of diet also reduces the number of physical and psychological…
RRT activation rate within a hospital or wards within a hospital are likely to be associated with specific factors regarding possible delay in escalation of care for deteriorating patients. This research is focussed on elucidating factors which may…
This study aims to assess the efficacy and safety of induction and consolidation therapy with Carfilzomib, Pomalidomide and Dexamethasone in subjects with relapsed or refractory multiple myeloma (MM) after prior first-line treatment in the EMN02/…
- Hypothesis#1 efficacy We hypothesize that a quick onset, and a predictable dose-response, good adjustability of analgesia can be achieved with inhaled ketamine. Hypothesis#2 safety Inhalation of nebulized ketamine might lead to a fast onset of…
Perfusion Angiography, in relation with known parameters, describes the ultimate prognostic model in revascularized Critical Limb Ischemia patients.
Our hypothesis is that high-dose, pulsatile sorafenib may exhibit improved efficacy with an acceptable toxicity profile compared to standard continuous dosing. AUC escalation cohorts are used instead of the conventional dose escalation cohorts,…
Daily showering followed by immediate application of emollient is better for the clinical outcome of mild to moderate AD in children, when compared to once weekly showering followed by immediate application of emollient.
MIA is a good alternative for the CA, with comparable diagnostic performance. It will lead to an increase in clinical autopsy rates, which have significantly decreased over the last decades in both academic and non-academic medical centers.
Primary aim: 1. To investigate whether differences exist in the mitochondrial energy generating capacity of skeletal muscle of statin users with SAMS compared to statin users without SAMS and controls (non-statin users). Secondary aims: 2A. To…
In line with a previous pilot study we hypothesize that 3MDR will significantly decrease PTSD symptom severity in treatment resistant veterans with chronic PTSD in comparison with treatment as usual.
The RAINBOW study: Rheumatoid Arthritis ImplemeNtation of Biological dose Optimization in real World
We hypothesize that a multifaceted implementation strategy can stimulate the use of tight control and bDMARD dose optimization in clinical practice, measured by decreased bDMARD use and non-inferiority on disease activity at 18 months.
Patients subject to MET review have a high in-hospital mortality (20%). Thus, understanding the outcome of patients within the first 24hr of MET review is important in developing quality improvement and interventional studies to reduce this…
The null-hypothesis predicts that Inlife is not feasible. The alternative hypothesis predicts that the Inlife intervention is evaluated as being feasible. We expect the alternative hypothesis to be true. Inlife will be feasible and minor revisions…
1) The knowledge of the legal aspects of health care and medical negligence/errors among medical residents is larger in the intervention group than for the control group 2) The flipped classroom model is effective as a teaching method in post…