1257 resultaten
The main objectives of this study are: • To gain insight into the effectiveness of the Healthy Working Approach on need for recovery in elderly care workers over one year. • To gain insight into the process of implementing the Healthy Working…
In this explorative study we will examine the impact of daily ischemic preconditioning on brachial artery endothelial function (measured as FMD%, before and after IRI) during 7 days in the non-shunt arm and lower limb in patients with end-stage…
Our first hypothesis is that both guided and unguided online CBT lead to a decrease in the severity of PCBD, PTSD, and depression symptoms. Our second hypothesis is that people allocated to the guided online CBT group will show a stronger decrease…
This study aims to assess the efficacy and safety of induction and consolidation therapy with Carfilzomib, Pomalidomide and Dexamethasone in subjects with relapsed or refractory multiple myeloma (MM) after prior first-line treatment in the EMN02/…
- Hypothesis#1 efficacy We hypothesize that a quick onset, and a predictable dose-response, good adjustability of analgesia can be achieved with inhaled ketamine. Hypothesis#2 safety Inhalation of nebulized ketamine might lead to a fast onset of…
We hypothesize that lower renal region or cerebral NIRS values are correlated with a higher incidence of postoperative AKI in this study population
Our hypothesis is that high-dose, pulsatile sorafenib may exhibit improved efficacy with an acceptable toxicity profile compared to standard continuous dosing. AUC escalation cohorts are used instead of the conventional dose escalation cohorts,…
Daily showering followed by immediate application of emollient is better for the clinical outcome of mild to moderate AD in children, when compared to once weekly showering followed by immediate application of emollient.
VIM-positive Pseudomonas aeruginosa can be found in other body sites besides throat and rectum, which are currently used as the standard surveillance culture sites.
Cerebral amyloid angiopathy is an important predictor for cognitive decline after intracerebral hemorrhage
Primary aim: 1. To investigate whether differences exist in the mitochondrial energy generating capacity of skeletal muscle of statin users with SAMS compared to statin users without SAMS and controls (non-statin users). Secondary aims: 2A. To…
We hypothesize that therapeutic drug monitoring of risperidone in children with an autism spectrum disorder and comorbid behavioral problems will reduce metabolic side effect burden, while retaining clinical effectiveness.
We hypothesize that clinicians exposed to this intervention are more likely to adopt SDM behaviors than clinicians who do not. A secondary aim is to evaluate whether patients perceive more involvement in the decision-making process.
I. Test whether psychological and psychophysiological indices of PC are differentially affected by fantasizing vs. mindfulness in remitted MDD patients and HC: Pre-and peri-intervention changes will be examined using within-subject and between-group…
We aim to compare the accuracy of ultrasound derived blood flow parameters from the carotid artery to pulse-contour derived cardiac output and non-invasive cardiac output measurements. Our motivation is to develop a non-invasive, radiation-free,…
We expect that mp-MRI, molecular urine test and Prostate Cancer Risk Calculator may be of additional value in differentiating between significant and insignificant cancers in men with an elevated PSA in the primairy diagnosis. If so, it will result…
The primary objective of this study is to explore the correlation between invasive and non-invasive haemodynamic variables and monitor the effect of treatment during admission for acute decompensated heart failure. In particular to investigate…
Research questions: To what extent does the subtype determined by means of the questionnaire (including algorithm) correspond with the subtype determined by a TCM expert?
The aim of this study is to characterize the proportion and extent of patients who return-to-work and who enter (partial) disability pension in a “labouring class” of patient infected by COVID-19, who were admitted to the hospital for medium- and/or…