3006 resultaten
We hypothesize that PARP inhibitors can potentiate radiation-induced tumor cell death in patients treated with PRRT. To determine the maximin tolerated dose (MTD) of this combination, a phase 1 dose-escalation study is needed.
• There is no difference in number of bonding failures between the direct and indirect bracket bonding methods • Patients favour indirect bracket bonding over direct bracket bonding • Brackets bonded with the indirect bracket bonding will have less…
Short hydration during cisplatin chemo radiation is significantly more effective than long hydration in preventing acute kidney injury
The aim of the pilot trial is to: 1. evaluate the potential effectiveness and effect size of the e-support program for parents of children with a chronic kidney disease; 2. to identify outcome measures most likely to capture potential patient…
Two doses of the Coronavirus virus-like particle subunit vaccine ABNCoV2 in SARS-CoV-2-naïve healthy adults is safe and well tolerated.
Laparoscopic gastrectomy will result in a lower post-operative burden by means of shorter post-operative hospital stay
The hypothesis of this study is that dosing everolimus 5mg twice daily(BID) instead of 10 mg once daily (QD) decreases the incidence of side effects, as a result of a lower Cmax while maintaining Cmin and AUC.
The aim of this present diagnostic study is to determine the accuracy by which we can detect residual disease after neoadjuvant chemoradiotherapy.
Postoperative pain management by using either regional continuous PVB or single shot ICNB is non-inferior to TEA regarding pain in patients undergoing thoracoscopic anatomical lung resection. Regarding QoR after surgery the unilateral regional…
We hypothesize that the HINTS+ test is more reliable than early MRI imaging in patients with acute onset continuous dizziness. As a result it is hypothesized that HINTS+ clinical examination leads to lower costs and an improvement in Quality of Life…
In the Netherlands, case managers play an essential role in the care chain for people with dementia living in the community. Because the profession has just been started, there is a lack of evidence-based practice to provide treatment for agitation…
The mean 12 months eGFR change between adult HIV-1 patients on TDF containing cART without reported NSAID/MRP4-i exposure will be greater than HIV-1 patients on TDF containing cART in the highest quartile of monthly cumulative DDD NSAID exposure (…
Compression therapy is not necessary after VNUS. Patients receiving no compression therapy after VNUS will have similar outcomes in post-operative pain, oedema, and HRQOL, post-operative complications, time to full recovery.
the quality of consultation can be improved
Het primaire doel van het onderzoek is om te onderzoeken of veranderingen over de tijd in monitorende metingen van cognitie en gedrag gerelateerd zijn aan functionele uitkomsten in pediatrische oncologie groepen. Overige doelen zijn het onderzoeken…
After epilepsy surgery an improvement of the sleep quality and structure can be expected as result of the disappearance or decrease of the daytime and or nocturnal seizures and the reduction of the amount of medication. After implantation of vagus…
Simular outcomes in patients with 4 implants compared with patients with 6 implants with respects to peri-implant bone level stability
- Six weeks of ESM combined with personalized feedback sessions, compared with treatment as usual (TAU), leads to a stronger reduction in fatigue symptoms (primary outcome clinical effectiveness). - This intervention also leads to improvements in…
The NTX intervention training leads to significant increase in both near and far transfer outcomes, in comparison with the effects of a training of an active control group.
Semi-structured interview study to get insight in parents’ experiences of daily use of a stander in young children with cerebral palsy to prevent hip dislocation. In addition, data will be used to identify barriers and facilitators to improve future…