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A higher percentage of patients with MRD levels <0.1% (MRD negativity) after up to 2 courses of induction chemotherapy plus quizartinib, as measured in the bone marrow using MFCM before start of consolidation therapy, compared to a historical…
Two hours of end-ischemic hypothermic oxygenated perfusion via both the hepatic artery and the portal vein is feasible and safe in resuscitating liver grafts procured from donation after circulatory death donors.
Consumption of the new developed GUM will decrease the incidence of upper respiratory tract infections (URTI) and/or decrease the duration of acute gastrointestinal tract infections (GITI) in Asian toddlers
Teres Major muscle transfer group will show significant better improvement in active abduction and external rotation than the LD group after 1 year.
The aim of this study is to investigate the immune response to the tetravalent MenACWY-TT vaccine administered as a second meningococcal vaccination and compare the booster response to MenC with the booster response to the monovalent MenC-TT…
Pre-operative comprehensive digital Cardiac Counseling (prehabilitation) will reduce the cumalative incidence of MACE at 1 year postoperatively in patients operated for a cardiovascular procedure.
We hypothesize that BCG vaccination may reduce hospital admission and improve the clinical course of symptoms of elderly people during the SARS-CoV-2 outbreak.
DOACs are non-inferior to LMWH with regard to the risk of ICH in patients with brain cancer requiring anticoagulation.
The null hypothesis will be that the prevalence of bruxism and TMD, in PD patients will be higher than in their peers without PD. Also, we hypothesized that factors as medication use, disease severity, psychosocial factors and lifestyle factors are…
Based on literature we assume a 20% day 30 mortality of patients admitted to the hospital ward with COVID-19. We aim to lower this day 30 mortality to 10%.
1) In what proportion of severe hypoxic COVID-19 patients on HFNC is invasive mechanical ventilation necessary? 2) In what proportion of severe hypoxic COVID-19 patients with an DNI code on HFNC results in progressive respiratory failure or death?
The hypothesis of this trial is that reusable catheters are as safe and efficient as single use catheters and will be cost-effective.
Does maternal diet influence the child’s intestinal microbiome via breast milk?
A dose of 75mg of intranasal ketamine lowers suicidal ideation
This proof-of-concept study aims to determine whether intervention in the preclinical phase in symptomatic patients at risk for RA is effective in progression from subclinical inflammation to clinically apparent persistent arthritis.
We will investigate the effects of high dairy intake on metabolic flexibility, glucose metabolism and insulin sensitivity, which are all important characteristics of (metabolic) health. We hypothesize that high dairy intake improves insulin…
1. There are differences of thermoregulatory behavior and thermo-physiology between healthy lean and obese subjects. 2. Healthy lean and obese individuals can be classified based on individual thermal preference, which is a result of distinct…
The amount of skin tension and the direction of highest skin tension is influenced by posture changes and the location of the body.
Operative treatment with additional concentrated bone marrow cells results in better fifth metatarsal stress fracture healing than operative treatment alone. We furthermore hypothesize that composition of bone marrow cells also contributes to…
We hypothesize a lung–protective mechanical ventilation using lower tidal volumes during general anesthesia for minimally invasive transthoracic esophagectomy to protect against postoperative pulmonary complications in patients undergoing minimally…