4440 resultaten
We hypothesize that PARP inhibitors can potentiate radiation-induced tumor cell death in patients treated with PRRT. To determine the maximin tolerated dose (MTD) of this combination, a phase 1 dose-escalation study is needed.
The null hypothesis of the primary outcome measure is that there will be no significant differences in DASH scores 6 months after surgery between patients who underwent plate fixation or intramedullary fixation with a TEN. The alternate hypothesis…
• There is no difference in number of bonding failures between the direct and indirect bracket bonding methods • Patients favour indirect bracket bonding over direct bracket bonding • Brackets bonded with the indirect bracket bonding will have less…
Short hydration during cisplatin chemo radiation is significantly more effective than long hydration in preventing acute kidney injury
Two doses of the Coronavirus virus-like particle subunit vaccine ABNCoV2 in SARS-CoV-2-naïve healthy adults is safe and well tolerated.
The diagnostic triage will be a simple and feasible way to improve the diagnosis and treatment of frail elderly with exercise induced dyspnoea and/or reduced excersie tolerance.
Postoperative pain management by using either regional continuous PVB or single shot ICNB is non-inferior to TEA regarding pain in patients undergoing thoracoscopic anatomical lung resection. Regarding QoR after surgery the unilateral regional…
We hypothesize that the HINTS+ test is more reliable than early MRI imaging in patients with acute onset continuous dizziness. As a result it is hypothesized that HINTS+ clinical examination leads to lower costs and an improvement in Quality of Life…
Subacromial disorders are considered to be the most common pathology affecting the shoulder. The optimal therapy for shoulder pain (SP) in primary care is yet unknown, since clinical history and physical examination do not provide decisive evidence…
We expect that parents involved in the program (as compared to controls) will be more involved in high qualitative communication on alcohol topics, have more confidence in discussing alcohol matters and greater efficacy to prevent their children…
the quality of consultation can be improved
Het primaire doel van het onderzoek is om te onderzoeken of veranderingen over de tijd in monitorende metingen van cognitie en gedrag gerelateerd zijn aan functionele uitkomsten in pediatrische oncologie groepen. Overige doelen zijn het onderzoeken…
Simular outcomes in patients with 4 implants compared with patients with 6 implants with respects to peri-implant bone level stability
- Six weeks of ESM combined with personalized feedback sessions, compared with treatment as usual (TAU), leads to a stronger reduction in fatigue symptoms (primary outcome clinical effectiveness). - This intervention also leads to improvements in…
The NTX intervention training leads to significant increase in both near and far transfer outcomes, in comparison with the effects of a training of an active control group.
We want to test the hypothesis that internet based guided self-help is not more expensive and not less effective than usual care for patients with phobias.
We hypothesise that the intervention group will significantly improve detachment by increasing daily physical activity and relaxation, compared to the control group receiving usual care (minimal intervention or company's current health…
Ultrasound-accelerated catheter-directed thrombolysis can reduce the posttrombotic syndrome incidence, improve quality of life and reduce medical costs in patients with acute primary iliofemoral deep vein thrombosis.
Semi-structured interview study to get insight in parents’ experiences of daily use of a stander in young children with cerebral palsy to prevent hip dislocation. In addition, data will be used to identify barriers and facilitators to improve future…
Determination of preoperative cell-free DNA and circulating tumor cells alone or in combination with each other in peripheral blood of patients with colorectal liver metastases can discriminate between patients who have a recurrence of metastatic…