4185 resultaten
An expectative management ('watchful waiting') is not inferior regarding the composite of mortality and/or necrotising enterocolitis and/or bronchopulmonary dysplasia in comparison with an early treatment regime in preterm infants with a…
In this RCT we investigate the effects of two school-based physical activity interventions (aerobic exercises versus coordinative exercises) in primary school children on executive functions and academic achievement. We hypothesize that both aerobic…
Circulating tumour cells can help to diagnose Non small cell lung cancer (NSCLC), making the painful and invasive procedure of a lungbiopsy and bronchoscopy unnecesary. However, for this, we need to harvest higher amounts of CTC's and in more…
1. Gatekeeper training is effective in enhancing relevant skills 2. Gatekeeper training will diminish rates of (attempted) suicides at regional level 3. The intervention is cost-effective relative to routine medical care
ADMA (asymmetric dimethylarginine) plasma concentrations are higher in persons with mild renal insufficiency compared to persons with normal kidney function. ADMA plasma concentrations are inversely proportional to renal perfusion and endothelial…
Lithium treatment potentially enhances survival and slows disease progression in ALS patients
Painreduction for 67% of patients with a locally advanced or local recurrent pancreatic carcinoma through a short radiotherapy scheme (single arm phase 2 study)
We hypothesize that patients with a HER2-negative primary tumor but with at least one HER2-positive CTC benefit from HER2 targeted treatment with trastuzumab
Several reasons for clozapine discontinuation are known, but the current evidence identifying patients who are at risk of discontinuation of clozapine is small and not always consistent. Also cultural differences may question if international…
High-intensity stress reduces cognitive performance (visuo-spatial learning) both for immediate and delayed recall.
The hypothesis is that minimal invasive surgical ablation through video assisted thoracoscopic surgey as a primary treatment in patients suffering from (longstanding) persistent atrial fibrillation is superior to transvenous catheter ablation
H1: the exercise intervention is effective in reducing (work-related) fatigue H2: the exercise intervention is effective in improving (work-related) self-efficacy, sleep quality, work ability, cognitive functioning, and aerobic fitness.
The hypothesis is that stratification of the referred population by the two referring screening radiologists using a validated design (BI-RADS, screening variant) can lead to a fast track workflow with only imaging tools, which would enable us to…
Wet-wrap treatment with diluted corticosteroids is more effective than wet-wrap treatment with emollients only
Betere patientveiligheidscultuur leidt tot een betere naleving van de richtlijnen op de OK om postoperatieve wondinfecties te voorkomen.
English: Platelet reactivity assays and thromboelastography can predict postoperative blood loss at 6 hours after combined coronary artery bypass grafting and valve surgery Dutch: Plaatjesreactiviteit en thromboelastografie kunnen postoperatief…
1. Measurement of salivary metanephrines is just as accurate as plasma metanephrines in detecting a pheochromocytoma or sympathetic paraganglioma. 2. Anxiety levels are elevated in patients with a pheochromocytoma or sympathetic paraganglioma
The dentifrice with natural ingredients (Verum) inhibit 10% less gingivitis compared to the placebo dentifrice over a period of 4 months in healthy subjects.