70 resultaten
To continue a risk-adapted stratification of therapeutic intensity, incorporating response to pre-operative chemotherapy, in all children with Wilms tumour and other renal tumours of childhood. To test the treatment hypothesis that doxorubicin is…
Early induction of labour being an effective intervention e.g. for the prevention of neonatal neurologic morbidity for fetus with established disproportionate intauterine growth retardation.
1. After treatment, patients of the experimental group will show less depression; 2. After treatment, patients of the experimental group will show better quality of life; 3. After treatment, patients of the experimental group will show less…
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Hormonal stimulation with r-FSH during IUI treatment will result in multifollicular growth in subfertile women with elevated early follicular FSH values.
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The systemic treatment of rheumatoid arthritis with anti-TNF-a is very successful. In a number of case reports varying success rates of intra-articular injections with the TNF-a blocking agent infliximab have been reported. In this study we want to…
anatomy sparing 2-incision total hip arthroplasty (THA) has a better functional outcome than conventional THA.
In MMC-children treated with CIC, the incidences of significant bacteriuria and pyelonephritic episodes are only slightly smaller in the group of subjects treated with LDCP compared to the group without LDCP.
This study aims to evaluate the baseline GH status, body composition and insulin sensitivity in (pre)pubertal short children born SGA. It also evaluates the effects of GH treatment on GH levels, body composition and insulin sensitivity. Furthermore…
It is postulated that the investigational treatment has superior efficacy based on observations of longterm remissions in a number of patients, although this has to be balanced against potentially higher toxicity.
Antioxidants or anticytokines may suppress the autoimmune reaction in orbital tissues in Graves' orbitopathy patients. Nul hypothesis: selenium and pentoxifilline are as effective as placebo in mild Graves' orbitopathy.
Does the use of alternatives to allogeneic blood (erythropoietin or reinfusion of autologous shed blood intra- and/or postoperatively) for patients undergoing elective total knee- or hip replacement surgery lead to continuous sparing of allogeneic…
Intrapartum fetal monitoring with the STAN-method (cardiotocograpy with ST-analysis of the fetal ECG) results in less neonates with metabolic acidosis and less interventions for fetal distress as compared to monitoring with cardiotocography in…
To compare the efficacy and tolerability of immediate optimal endocrine adjuvant therapy versus standard chemotherapy (5 endocrine therapy in pre- and perimenopausal patients with ER and/or PR courses FE90C) followed by the same positive primary…
Administration of probiotics to pregnant women from an atopic family and subsequently to their high-risk newborns results in prevention of the incidence of or in a decrease of the severity of atopic disease during infancy.
Non-inferiority hypothesis: observation is not inferior to operation with respect to the mean of pain and discomfort during 3 years follow-up.
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Resuscitation after birth with 30% oxygen reduces oxidative stress and is safe in preterm infants.
1. The incidence of falls in the elderly can be reduced by identifying elderly at high risk of falling followed by a systematic multidisciplinary examination of the causes of faling and by taking tindividual preventive measures (transmural health…