1250 resultaten
In this RCT we investigate the effects of two school-based physical activity interventions (aerobic exercises versus coordinative exercises) in primary school children on executive functions and academic achievement. We hypothesize that both aerobic…
A higher percentage of patients with MRD levels <0.1% (MRD negativity) after up to 2 courses of induction chemotherapy plus quizartinib, as measured in the bone marrow using MFCM before start of consolidation therapy, compared to a historical…
Two hours of end-ischemic hypothermic oxygenated perfusion via both the hepatic artery and the portal vein is feasible and safe in resuscitating liver grafts procured from donation after circulatory death donors.
At two-year follow up, employees of the intervention schools report significantly lower levels of work stress and work stress risks as compared to employees of the control schools
De hypothese is dat bekkenfysiotherapie de obstipatieklachten bij kinderen gunstig kan beinvloeden.
It is hypothesized that SADI after sleeve gastrectomy for additional weight loss is superior to a gastric bypass as secondary procedure
A levonorgestrel releasing intrauterine system (LNG-IUS) and endometrial ablation are two frequently used methods for the treatment of menorrhagia, of which the first can be applied by a general practitioner or a gynaecologist, whereas the second is…
Emerging techniques measuring oxidative APAP metabolites and microRNA-122 (miR-122) could make it possible to detect paracetamol induced liver injury earlier and more precisely than currently used paracetamol plasma concentrations and clinical…
A dose of 75mg of intranasal ketamine lowers suicidal ideation
The actual ERAS statement regarding intra- and postoperative analgesia recommends to not use thoracic epidural catheters in laparoscopic surgery anymore as a gold standard. This cohort study will investigate an alternative possibility of pain…
1. There are differences of thermoregulatory behavior and thermo-physiology between healthy lean and obese subjects. 2. Healthy lean and obese individuals can be classified based on individual thermal preference, which is a result of distinct…
The amount of skin tension and the direction of highest skin tension is influenced by posture changes and the location of the body.
To compare a ventilation strategy that uses conservative targets (PaO2 55-80 mmHg (7.3-10.7 kPa)) with one that uses conventional oxygenation targets (PaO2 110-150 mmHg (14.7-20 kPa)) for arterial oxygenation. Primary endpoint is all-cause mortality…
1. Gatekeeper training is effective in enhancing relevant skills 2. Gatekeeper training will diminish rates of (attempted) suicides at regional level 3. The intervention is cost-effective relative to routine medical care
The objective of the proposed study is the intraoperative detection of tumor tissue of peritoneal carcinomatosis of colorectal origin by using a near-infrared fluorophore, 800CW, conjugated to bevacizumab resulting in a bevacizumab-IRDye800CW…
The primary hypothesis is that an association exists between the presence of a niche and abnormal uterine bleeding in women who had a previous caesarean section.
ADMA (asymmetric dimethylarginine) plasma concentrations are higher in persons with mild renal insufficiency compared to persons with normal kidney function. ADMA plasma concentrations are inversely proportional to renal perfusion and endothelial…
Obesity is significantly associated with Atrial Fibrillation (AF), and, interestingly, if obese patients loose weight, AF dissapears in 50% of the cohort. On the other hand, adipose tissue (AT) functioning alters up weightchange. Therefore we…
Lithium treatment potentially enhances survival and slows disease progression in ALS patients