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1) Implementing TIPP will prevent acute emergency room (ER) visits, rehospitalisations and inappropriate referrals 2) Implementing TIPP improves transitional patient safety culture 3) Although TIPP aims at reducing transitional incidents,…
About 25% of patients who suffer from a subarachnoid hemorrhage or intraventricular hemorrhage have a vital indication for an external ventricular or lumbar drain to aleviate the intracranial pressure. About 5-10% of these patients develop a…
The present mode of (tonic) SCS is accompanied by paraesthesia in the area of stimulation. Recently, a new mode of SCS has been developed which makes it possible to apply spinal cord stimulation without paraesthesias. This mode is called burst…
This study will use a Randomized Controlled Trial (RCT) to evaluate the effectiveness and underlying mechanisms of the video game Mindlight, a newly developed anxiety-reducing training for children. Mindlight and a control game will be played for…
Despite appropriate antimicrobial therapy and supportive care, septic shock is still a major cause of mortality and morbidity. Within the last decade, a broad body of evidence suggests a potential role for mesenchymal stromal cell (MSC, a…
Usage of the 'Moveosiphon' sonothermal sink disinfection device prevents leads to a persistant decrease in colonization with multiresistant Pseudomonas aeruginosa
Objectives: The aim of this study is to investigate the feasibility of a computer-based cognitive training (working memory training) in a relative old and cognitive impaired population of MCI patients. We will examine the effect of this cognitive…
Blended eHealth treatment is evenly effective and more cost-effective than treatment as usual.
The application of contrast-enhanced ultrasound can accelerate thrombolysis in patients with acute peripheral arterial occlusions.
Whereas initially the concept of burn-out was restricted to professions in the human services domain, over time the scope has been broadened to all sorts of professions and occupational groups (Schaufeli et al., 2002). Research indicates that full…
Brown adipose tissue (BAT) is thought to be involved in human glucose and lipid metabolism, however the mechanisms by which this adipose tissue is activated remain to be elucidated. Recent data in db/db mice have suggested that oral butyrate has…
1) FeNO, blood eosinophils and total IgE will have a moderate diagnostic accuracy to detect sputum eosinophilia in adult-onset asthma patients. 2) There will be differences in accuracy between sub-groups of patients.
Electrophysiological connectivity between ATN and cortical zones involved in the epilepsy of the patient in question relates to treatment response
After implementation of the intervention the sustainable workability of teachers and staff in the intervention group will be significantly higher than the sustainable workability of those in the control group, both direclty after intervention and in…
Taken together, a profound understanding of the [18F]FDHT pharmacokinetics could lead to an optimization of the [18F]FDHT PET diagnostic potential; integration of DCE MRI and PET parameters would allow for a clinically feasible method with PET-MRI.…
The hypothesis is that modarate and late preterm infants at age 12 reported more symptoms consistent with asthma and use more asthma medications, as well as a poorer lung function, exercise capacity and Lung Clearance Index than healthy peers.
Short empirical treatment with a anti-pseudomonal carbapenem in hematology patients with unexplained fever during neutropenia is non-inferior to extended treatment with regard to treatment failure.
The effectiveness of the commercial video game Journey in preventing depression will be tested in a Dutch sample of adolescents with elevated depressive symptoms. In an RCT design the effectiveness of Journey will be compared to the effectiveness to…
The main aim of this project is to conduct a randomized controlled trail (RCT) to evaluate the effectiveness of the videogame Dojo as an intervention for anxious-aggressive youths in residential treatment. The effectiveness of Dojo will be compared…