88 resultaten
An online motivational interviewing intervention which includes a virtual coach results into the higher levels of participation, evaluation and higher effects on intrinsic motivation, commitment and physical activity behaviour, compared to online…
We hypothesize that CTX patients, when untreated for a short period, differ from matched healthy controls in the response to a test meal. CTX patients are expected to have lower postprandial GLP‐1 and insulin levels with higher plasma glucose and…
Vitamin D supplementation will improve glycemic control in patients with type 2 diabetes melliuts.
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1. SNS is more effective than BOTOX® 100 U as assessed by the difference between treatment groups in the proportion of idiopathic OAB patients with a positive treatment response on the Patient Perception of Bladder Condition (PPBC) at Week 12…
We hypothesis that early surgical intervention results in less pain over the study period and is more cost-effective than the optimal current step-up practice.
The current study evaluates whether accurate optical diagnosis of small colorectal polyps (<10mm) in vivo in a non-expert setting can be achieved, resulting in the omission of formal histopathology, which could make colonoscopy more efficient…
Functional grasping of selected objects from the ARA test (10cm cube, 2.5 cm cube, 6 mm ball bearing and 1,5cm marble) can be improved by combining robotics and electrical stimulation by means of effective self-learning control algorithms.
To prospectively assess the efficacy, feasibility and safety of a systemised endoscopic surveillance protocol in large multicentre HPS cohort.
Formalization of the current guidelines on VTE treatment duration with VKA, by means of using a VTE recurrence prediction model in patients with venous thrombo-embolism, will optimize its cost-effectiveness compared to care-as-usual. Only patients…
The first two exons of TRPV1 are deleted in the most common mutation found in cystinosis patients: A large 57 kb deletion. We aim to study TRPV1 expression in cystinosis patients both homozygous and heterozygous for this deletion.
The fenestrated Anaconda endograft is safe for durable exclusion of juxta and suprarenal AAA.
Prevention and treatment of venous thromboembolism (VTE) with low-molecular-weight heparins (LMWHs) is confirmed to be at least as effective as with unfractionated heparin (UFH). In comparison to UFH, the LMWHs have improved pharmacokinetics, ease…
The effectiveness of a school-based indicated depression prevention program ('Op Volle Kracht') will be tested in a Dutch sample of adolescent girls with elevated depressive symptoms (aged 12-14 years). It is expected that the adolescent…
Although vitamin D is well known for its function in calcium homeostasis and bone mineralisation, several studies have shown an effect on pulmonary function and incidence of airway infections. Vitamin D deficiency is a common problem in patients…
The software of the PlustoptiX devices is developed for pupils up to 7.8 to 8mm in size. In the study “a double blind randomized study on the efficacy of cyclopentolate 1% and tropicamide 1% in children (MEC nr NL32954.098 /1010-077; NTR 2476),…
We hypothesize VOC signatures to discriminate between critically ill patients: 1. With and without sepsis; 2. With or without pneumonia; 3. With a gram positive or gram negative infection; 4. With and without organ failure, including: A. Acute lung…
It is expected that dopaminergic antagonism by haloperidol 2mg or 3mg wil result in specific inhibition of both bias and disengagement related activity as measured by EEG in combination with computertasks. Specifically, we expect that, dopamine…
High dose of oral administration of omega-3 fatty acids ameliorates hepatic steatosis and insulin sensitivity in morbidly obese patients undergoing LRYGBP.