82 resultaten
By using a surgical safety checklist, the incidence of postoperative complications will decrease.
To investigate the newly developed method to study lung density changes using CT-scan, in a small patient population. The relationship between radiation induced lung density changes and dose distribution/tumor location will be investigated.
The behavioural effects of an antihistamine is apparent in the evening after an evening dose, but will be smaller in the morning after a morning dose condition due to the excessive release of histamine shortly after awaking.
This non-inferiority study specifies as a null hypothesis that ICG enhanced NIRF imaging is inferior in detecting sentinel lymph nodes compared to the current standard treatment (technetium-99m combined with Patent Blue).
Does computer tailored feedback improve the lifestyle of COPD patient?
Improvement of favourable outcome by consecuetive treatment of tranexamic acid before aneurysm treatment with switch to acetylsalicylic acid short before start of treatment and continued for two weeks.
Chronic heart failure (CHF) and chronic obstructive pulmonary disease (COPD) are important causes of morbidity and mortality. The prevalence and incidence of COPD as well as CHF are still rising. CHF is an important co-morbidity in COPD and vice…
This study aims to test the efficiency and cost-effectiveness of a brief collaborative care intervention, in long-term users (>9months) of antidepressants in the general practice. This intervention will contain a patient-tailored treatment…
Acute challenges with cocaine and cannabis will induce two opposing dopaminergic states in the brain. Cocaine will stimulate dopamine release leading to hyperdopaminergia whereas cannabis will reduce central dopamine levels resulting in…
Recent data showed for the first time that IgE-ACPA antibodies have a direct biological immune response in mast cells of IgE-ACPA+ RA patients. Subsequently, mast cell targeting agents, such as anti-IgE therapy have rationale for application in RA…
Compared to standard care, Peer Driven Fellow Care combined with standard care will result in significantly less drop out and improved flow in the social rehabilitation process for homeless people, as well as in significant improvements in…
We hypothesize that a multidisciplinary group-based, self-management intervention is more effective on functioning in daily living and more cost-efficient than the active control group in patients with generalized osteoarthritis (GOA).
We hypothesize that the intervention will prove to be more effective than the control condition in achieving significant body weight loss at 3 months; We expect to observe significant changes in metabolic, psychological and behavioural parameters at…
Dronabinol impairs driving performance in light cannabis users, but not in heavy users, because of tolerance to the impairing effects.
Pre-operatieve training in oudere orthopedische patienten - een experimenteel en klinisch onderzoek.
Pre-operative training improves physical recovery after surgery for lumbar spinal stenosis.
Results of WArts Randomised Treatment Study of 2006 show that the best treatment for common warts is cryotherapy compared to salicylic acid or awaiting policy (after 13 weeks). In case of plantar warts none of either treatments (cryotherapy or…
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To assess whether the NOPHO- AML 2004 protocol can be used for the treatment of Dutch and Belgian children with newly diagnosed AML, whereby the cumulative dose of the possible cardiotoxic cytostatic antracyclines is lowered without increasing the…
Acute normovolemic hemodilution during coronary artery bypass surgery involving normothermic cardiopulmonary bypass (CPB) leads to dysfunction of cerebral autoregulation and therefore contributes to neurological morbidity after cardiac surgery.
The null hypothesis for this study is that endovascular treatment for acute ischemic stroke with onset of less than six hours in patients with a symptomatic intracranial proximal arterial occlusion, leads to a similar distribution of functional…