7836 resultaten
We hypothezise that methotrexate and azathioprine will be equally effective for the treatment of severe atopic dermatitis.
We hypothesize that the phenotypic profiles of the ASM layer at the gene-level is different between asthmatic and healthy patients, is associated with measures of variable airways obstruction and with the inflammatory infiltrate within and outside…
EN - Unrelieved chronic pain represents a major problem for individual patients and is also a socio-economic burden for health services and the community at large. Although the etiology of musculoskeletal chronic pain following trauma is not well…
rt-PA administration by retinal branch vein way in CRVO patients improves final BCVA.
The purpose of this study is: 1. To investigate the differential effectiveness of group and individual parent training in PRT on opportunities created by parents and social initiations of children with Autism Spectrum Disorder (ASD). 2. To…
We hypothesize that a combined lifestyle intervention added to usual care will result in a 5 kg or 5% weight reduction resulting in a greater reduction in knee pain, an increase in the quality of life, prevent structural progression, and is cost-…
Thermoregulation in patients with spinal cord injury and cold sensations, an explorative pilot-study
We hypothesize that patients with regular complaints of cold sensations have impaired thermoregulatory responses to changes in environmental temperature. We expect that they are not able to stabilize their core body temperature during changes in…
In this study the hypothesis will be tested that gemcitabine has a radiosensitizing effect in addition to 131I-MIBG therapy which will lead to increased anti-tumour effect in neuroblastoma.
The combination of DLI with bortezomib given before and after the DLI improves the Graft versus Myeloma effect without effect on the Graft versus host disease
Hepatic steatosis is becoming a large health burden in both Western and non-Western societies. There is a need for specific diagnostic tools that can distinguish between patients with significant steatosis and those without whilst simultaneously…
We hypothesize that standardized training for endoscopist comprising endoscopic diagnosis followed by a therapeutic plan and high-quality endoscopic resection performance will reduce the number of recurrence after resection of large non-pedunculated…
Based on the human milk composition, Nutricia Research has developed a new infant formula with a new fat blend, more similar to that of human milk. This new formula is currently being studied for safety and its effects on growth. The comparator used…
By using weekly the clinical rule reporter as the medication review system, the number of hospital readmissions in older patients (> 60 years) will be reduced with 5% (from 20% to 15%). For the Netherlands this may translate into prevention…
There is no relationship between the duration of the procedure under PSA and the incidence of atelectasis and/or respiratory symptoms.
Time to recurrence of sustained VT (longer that 30 seconds or with hemodynamic instability) or VF with or without documented ICD therapy (shock or ATP) for VT of VF will be longer in patients randomized to substrate based ablation than in patients…
The COL3A1 polymorphism is a inheritable genetic defect, responsible for the increased susceptibility to pelvic organ prolapse in women.
Freezing of gait (FOG) is a particularly disturbing and potentially harmful symptom occurring in a majority of people with Parkinson's Disease (PD) over the course of disease. External cues, such as a metronome or bars on the floor, aid in…
The hypothesis is that offering CBT in a group format while discontinuing antidepressant medication will reduce the high relapse rates in remitted anxiety disorder patients who discontinue pharmacological treatment.
Repetitive ePIPAC-OX as a palliative monotherapy is a feasible, safe, tolerable, and potentially effective treatment for isolated unresectable colorectal peritioneal metastases, with low and predictable costs and a low systemic uptake of oxaliplatin…
We hypothesize that exercise training improves maximal exercise capacity in adult patients with a systemic RV. Moreover, we hypothesize that exercise training decreases serum NT-proBNP levels and increases quality of life in adult patients with a…