521 resultaten
Gastric fluid volumes in patients with a 6-4-0 pre-operative fasting regime are comparable to patients with a 6-4-2 pre-operative fasting regime
The main clinical challenge remains to identify patients who may benefit from aggressive local treatment (stereotactic radiotherapy, SBRT) of soft tissue oligometastases: for which patients can systemic treatment be postponed? Patients who are…
We hypothesize there is a difference in CPM between the protocols
Wij stellen de hypothese dat een ontstekingsremmend voedingspatroon (AIDP) een gunstig effect heeft op het darmmicrobioom (diversiteit en permeabiliteit), waardoor het globaal functioneren (gemeten met Outcome Questionnaire 45, OQ-45) en de…
We hypothesize that PARP inhibitors can potentiate radiation-induced tumor cell death in patients treated with PRRT. To determine the maximin tolerated dose (MTD) of this combination, a phase 1 dose-escalation study is needed.
• There is no difference in number of bonding failures between the direct and indirect bracket bonding methods • Patients favour indirect bracket bonding over direct bracket bonding • Brackets bonded with the indirect bracket bonding will have less…
Short hydration during cisplatin chemo radiation is significantly more effective than long hydration in preventing acute kidney injury
The primary research questions are: 1. To what extent does a 4 week ReHab-TOAT regime lead to improvement of arm function in chronic stroke patients with either a severely or moderately affected arm-hand? 2. To what extent is any improvement of arm…
Blue light glasses can manipulate (i.e., inhibite) body melatonine production to re-adjust the circadian rhythm of shift workers, thereby having the potential to enhance viglance, cognitive function, and positive mood during night shift work.
Primary Objective: 1.To investigate whether daily electrical stimulation of gluteal and hamstring muscles combined with usual care is more effective in reducing recurrences of PUs than only usual care in individuals with chronic SCI, who often have…
There are multiple ways of weaning from venovenous ECMO support
The aim of this study is to evaluate the effects of platelet transfusions on hemostatic parameters in thrombocytopenic hematology patients and to identify other determinants of hemostasis, which may contribute to clot formation and clot strength.
We hypothesize that there will be a significant difference in anterior translation of the humeral head between patients and healthy objects. Secondly we hypothesize that the inter- and intra-rater reliability of the HHC test will be fair to good.…
Metabolic syndrome is a cluster of conditions that are associated with insulin resistance, hyperinsulinemia and type 2 diabetes (T2D). Pathophysiological conditions characterized by insulin resistance and hyperinsulinemia can lead to several, often…
The primary objective is to investigate the effectiveness of a personalized 2-year multidomain lifestyle intervention on cognitive performance in older adults at risk of cognitive decline.
It is hypothesized that the orientation of the lower limb joints are not parallel to the walking direction and that a standing measure is highly correlated with the orientation during the standing, load bearing, phase of the gait cycle.
The hypothesize is, that treatment with induction chemotherapy will lead to a 15% increase of the R0 resection rate compared to treatment with neoadjuvant chemoradiotherapy and surgery alone.
European randomised controlled multi-centred implementation trial amongst 24,000 individuals, at high risk for developing lung cancer, evaluating whether it is safe to have risk-based less intensive screening intervals after a negative baseline CT.
We hyopthesize that in SCCH patients 3-monthly pamidronate decreases locally increased bone turnover (measured by Na18F-PET scans) and thereby decreases pain, and leads to improvement in shoulder girdle function, quality of life, physical and work…
Patientes with mental disorders will experience more often sexual problems and a need for help for these problems compared to healthy controls