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Focusing on disease-modifying rather than etiologic mechanisms may accelerate the development of novel therapies and complement current research initiatives on causative mechanisms and curative therapies.
Education on guidelines, combined with quality targets within the accreditation procedure improves quality of antibiotic prescribing
Patients with Type 2 diabetes have been shown to have an increased risk for developing cancer, especially obesity related cancers. There is some evidence that within the class of sulfonylureas there is a difference in cancer risk; gliclazide could…
Different prevention strategies are used internationally to prevent Early-onset Group B haemolytic streptococcus infection (EOGBS). However, none of the preventive EOGBS strategies in place at present result in the complete prevention of EOGBS,…
There is no difference between CT- and MRI-based Patient specific matched instruments for total knee arthroplasty
The primary objective of this study is to determine whether thrombectomy combined with ischemic postconditioning after PCI leads to a smaller myocardial infarction compared to standard therapy.
The purpose of this research is to acquire a better understanding of the pain experience and the recovery of children between 1.5 and 5 years old who underwent a tonsillectomy/adenotonsillectomy. Primary research question: What is the influence of…
The objective of the study is to investigate the effect of virtual reality training, given between 2 weeks and 6 months after stroke, on participation and subjective physical functioning in independently living patients.
Spinal anesthesia induces several alterations in normal brain processes. Firstly, loss of afferent information increases pain sensitivity. In our previous study on the effects of spinal anesthesia (P11.221) we showed that subjects felt more pain…
Induced hypothermia to 32-34 degree Celsius using NovathermTM with extracorporeal iLA-Activve MinilungTM allows for a reduction in minute volume ventilation needed for adequate gas exchange in patients with ARDS, with a concomitant decrease in work…
Faecal transplantation from a healthy donor can restore the dysbiosis present in adolescents with refractory IBS, thereby inducing improvement of the IBS complaints.
To determine if treatment with rhEPO reduces the need for top-up transfusions in neonates with red cell alloimmunization treated (with or without intrauterine transfusions).
It was hypostasized that the use of the online tool www.runfitcheck will cause a 10% behavior adjustment in runners.
Objective of the study: The research aims to 2 new forms of treatment for patients with comorbid PTSD as a result of multiple and repeated abuse in childhood to assess and compare Imaginary Exposure. The expectation is that these new forms of…
A 4 hour intervention period with the new disease-specific tube feed will result in a better plasma glucose profile as compared to an isocaloric standard tube feed.
Tamoxifen and endoxifen serum concentrations are linearly related to DBS concentration
The primary endpoint is to evaluate the use of Souvenaid in patients with early AD in real world clinical practice by assessing the effect of Souvenaid on patients’ functioning on instrumental activities of daily living (IADL) as perceived by the…
The aim of this phase I study is to assess the extent of intestinal absorption of rivaroxaban and dabigatran etexilate in adult patients with short bowel syndrome requiring long-term TPN.