642 resultaten
Systematic, population-based Chlamydia Screening will be able to bring down the prevalence of infections and incidence of longterm complications, provided participation rates are sufficient.
Synflorix (PCV10) and Prevenar-13 (PCV13) are comparable in inducing cellular and humoral immune responses in Dutch infants for the 10 overlapping serotypes in the vaccines. Differences are expected for three serotypes that are present in Prevenar-…
OBJECTIVE: To evaluate the immediate and longer-term effects of early cognitive rehabilitation on cognitive performance and self-reported symptoms/functioning in patients with low-grade gliomas and meningiomas, in a prospective randomized trial.…
In this explorative study we will examine the impact of daily ischemic preconditioning on brachial artery endothelial function (measured as FMD%, before and after IRI) during 7 days in the non-shunt arm and lower limb in patients with end-stage…
Different studies have shown that a hunter-gatherer type diet is effective in improving glucose regulation and lipid profile. I want to investigate if the hypothese that this type of diet also reduces the number of physical and psychological…
RRT activation rate within a hospital or wards within a hospital are likely to be associated with specific factors regarding possible delay in escalation of care for deteriorating patients. This research is focussed on elucidating factors which may…
Before we start with our research on assessing the diagnostic value of TMS-EEG in epilepsy, we perform this pilot study to investigate a number of methodological aspects. To be able to develop a sound protocol these aspects need to be explored in…
This study aims to assess the efficacy and safety of induction and consolidation therapy with Carfilzomib, Pomalidomide and Dexamethasone in subjects with relapsed or refractory multiple myeloma (MM) after prior first-line treatment in the EMN02/…
The aim of this study is to develop and evaluate a training program for CHWs in early detection or recognition of HIV suspected oro-facial lesions and to build their capacity and skill in mobilizing the community on HIV suspected oro-facial lesions…
- Hypothesis#1 efficacy We hypothesize that a quick onset, and a predictable dose-response, good adjustability of analgesia can be achieved with inhaled ketamine. Hypothesis#2 safety Inhalation of nebulized ketamine might lead to a fast onset of…
Perfusion Angiography, in relation with known parameters, describes the ultimate prognostic model in revascularized Critical Limb Ischemia patients.
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Main question: What is the value of the propensity for reinvestment (measured by the Movement Specific Reinvestment Scale) in predicting the functional mobility (measured with he Rivermead Mobility Index) of stroke patients after 15 weeks of…
Our hypothesis is that high-dose, pulsatile sorafenib may exhibit improved efficacy with an acceptable toxicity profile compared to standard continuous dosing. AUC escalation cohorts are used instead of the conventional dose escalation cohorts,…
The aim of this study is to validate the Dutch versions of the PainDETECT questionnaire PD-Q and the ‘Douleur neuropathique en 4 questions’ (DN4) for use in primary and specialist medical care settings for patients with LBP and NSP and patients with…
Treatment starting with a low dose dipyridamole reduces the side-effect headache with 25%.
Daily showering followed by immediate application of emollient is better for the clinical outcome of mild to moderate AD in children, when compared to once weekly showering followed by immediate application of emollient.
The depression prevention program ("Op Volle Kracht") will be delivered by teachers in the school curriculum in schools with adolescents from high-risk background. It is expected that adolescents who receive the interventions will show…
Primary aim: 1. To investigate whether differences exist in the mitochondrial energy generating capacity of skeletal muscle of statin users with SAMS compared to statin users without SAMS and controls (non-statin users). Secondary aims: 2A. To…
In line with a previous pilot study we hypothesize that 3MDR will significantly decrease PTSD symptom severity in treatment resistant veterans with chronic PTSD in comparison with treatment as usual.