332 resultaten
Primary Objective: The identification of (somatic and psychological) risk and protective factors for postoperative recovery, including the development of chronic post operative pain (CPSP), defined as persistent pain 3 and 12 months after the…
Systematic, population-based Chlamydia Screening will be able to bring down the prevalence of infections and incidence of longterm complications, provided participation rates are sufficient.
Synflorix (PCV10) and Prevenar-13 (PCV13) are comparable in inducing cellular and humoral immune responses in Dutch infants for the 10 overlapping serotypes in the vaccines. Differences are expected for three serotypes that are present in Prevenar-…
Training staff of severe mentally ill patients in stimulating a healthier lifestyle (more exercise, a healthier diet) of their patients will improve patients' metabolic health, decrease depressive symptoms and improve quality of life, at…
Red pepper might prevent reduction of energy expenditure and elevation of hunger as a result of energy intake restriction.
Recent research shows that obesity is associated with changed bowel flora composition with a relative abundance of the two dominant bacterial divisions, the Bacteroidetes and the Firmicutes. Interestingly, this specific bacteria associated condition…
1. The primary research inquiry being raised concerns anaesthesia related causes: Is it possible that adapting an amount of Sevoflurane, from 1 MAC (minimum alveolar concentration) (2,5 vol%) to ½ MAC (1,25 vol%) in an MRI scan can reduce the…
Publishing a guideline is not enough. An implementation strategy is needed to improve pain reporting, pain measurement and adequate pain therapy.
Higher occlusion rate in the EVLA group seen at 1 week postoperative. More recurrences seen in the VNUS group seen at long term. No differences in short term recovery results between both groups.
Clinically, children with syndromic craniosynostosis seem to have an increased risk of learning disabilities and behavioral problems in comparison with the general population.
The OptiScanner provides accurate blood glucose levels in critically ill patients.
1. Volume intervention by a diuretic and moderate sodium diet potentiates the antiproteinuric effects of aliskiren in patients with residual albuminuria during conventional RAAS-blockade; 2. Aliskiren neutralizes the reactive rise in plasma renin…
Chronic Obstructive Pulmonary Disease (COPD) is a chronic, progressive lung disease. The prevalence and associated costs of COPD are projected to increase the upcoming decades. The treatment of COPD aims to reduce risk factors, prevent disease…
Diskus is superior to Elpenhaler with regard to ease of use, preference and satisfaction.
The addition of metronomic cyclophosphamide to standard 2nd line treatment with everolimus will improve progression free survival of patients at 4 months from the reported value of 50% to 70% in patients with mRCC.
In RA patients that achieved disease remission by treatment with the combination of a csDMARD and anti-TNF, there is a difference in (cost-)effectiveness when medication is tapered according to strategy A (csDMARD first) compared to strategy B (anti…
Our hypothesis is that reverse arthroplasty has a better functional outcome and patient satisfaction than hemi-arthoplasty in patients with a three or four part proximal humerus fracture.
Postpartum urinary retention (PUR) is a complication with a varying prevalence, from 0.5 - 18%. For asymptomatic PUR, i.e. the ability to void but with a post residual volume (PVRV) of ≥150 ml, the estimation of prevalence is between 10-45%.…
Inhibition of CYP2D6 enzymes by SSRIs may lead to reduced endoxifen plasma concentrations and thereby possibly influence tamoxifen treatment outcome. Paroxetine is a potent CYP2D6 inhibitor and strongly reduces endoxifen plasma concentrations.…
This study will investigate whether 24 hour dopamine infusion reduces the need of hospital admission for patients with exacerbation heart failure.