29 resultaten
Assess the safety and tolerability of single ascending IV bolus doses of ABP-700
Patients who received CBM-I training will start their exposure therapy with lower anxiety levels, and their anxiety levels will reduce faster compared to patients that receive a placebo training.
Onlay and sublay mesh reinforcement after midline laparotomies in patients with an increased risk for the development of incisional hernias (IHs) resulted in less IHs compared to patients that received the conventional closure technique at two years…
Primary Objective: Investigate the effect of modafinil (200 mg) and caffeine (300 mg) on vigilance in low, medium and high caffeine consumers during the circadian trough in order to determine: - To what extend vigilance during the circadian trough…
To determine the role of 5-HT2 and 5-HT1A receptors in learning and memory. It is expected that: 1. An acute dose of MDMA will produce impairments on laboratory measures of learning and memory; 2. MDMA-induced memory impairment will be reversed…
Cabozantinib improves overall survival in patients with hepatocellular carcinoma compared with placebo
Intranasal administration of palivizumab is safe in healthy adult volunteers
The main objective of the human dietary intervention study is to investigate the beneficial health effects of food products containing various combinations of an equivalent of 400 grams vegetables and fruits in healthy volunteers. This will be…
Varenicline reduces craving to cocaine and/or impulsivity in human cocaine users.
The main hyothesis of the experiments is that a dual action antidepressant (duloxetine) modulates functions in specific brain areas involved in the processing bias of emotional stimuli in the context of neutral versus depressed mood.
Nasal administration of palivizumab in late preterm infants reduces RSV infection
•Bicruciate preserved tibia tray for TKA is at least as efficient and safe as the conventional tibia tray for TKA with elimination of the ACL. •TKA with the use of Signature™ alignment guide is at least as efficient and safe as TKA with the use of…
We hypothesize that exposure to the user-tailored, dynamic lighting condition will stabilize or reduce alcohol consumption and craving in comparison to a control condition with regular lighting.
Approximately 1/3 of persons with IGT develops type 2 diabetes mellitus in 5-10 years time. Acarbose is an alpha-glucosidase inhibitor decreasing post-prandial glucose levels, without the risk of hypoglycemia. The prevention of diabetes with…
The primary objective of the study is to examine whether the WhiteTeeth app used by orthodontic patients aged 12 to 16 improves oral health behavior and oral hygiene. Primary outcomes of this RCT are dental plaque levels, gingival bleeding upon…
1) Pre-sleep whey protein ingestion stimulates overnight muscle protein synthesis rates 2) Pre-sleep casein protein ingestion stimulates overnight muscle protein synthesis rates 3) Pre-sleep whey and casein protein do not differ in their impact on…
-We expect that the youth who receive an active CBM training on top of care-as-usual show a greater reduction in cannabis or alcohol misuse at follow up when compared their general population peers. -We expect that CBM training works by reducing…
We hypothesized that methylphenidate will improve certain aspects of language comprehension and creativity.
Modulation of phosphate intake can affect the antiproteinuric efficacy of RAAS-blockade therapy in CKD patients
The implementation of antimicrobial coatings in health care results in an improved hygienic environment to support patient recovery and lowers the risk of a health care associated infection.