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Effect van lage dosis radiotherapie op pijn bij milde heupartrose

Subjectieve en objectieve evaluatie van het therapeutische effect van laag-gedoseerde radiotherapie op de pijn en functiebeperking ten gevolge van milde artrose van de heup

RAR-CLA and cognition

Daily supplementation of 3.5g RAR-CLA will slow down cognitive decline as compared to placebo

The surplus value of Doppler in Hemorrhoid Artery Ligation procedure.

Standard localized ligations are as feasible as doppler-guided ligations of hemorrhoid arteries.

Clinical trial of dabigatran on airway inflammation and coagulation in severe asthma.

We hypothesize that in patients with severe corticosteroid dependent asthma Dabigatran etexilate will: 1. Reduce airway inflammation; 2. Improve asthma control and pulmonary function; 3. Reduce hypercoagulability in the airways.

Fluoxetine and the developing brain.

Administration of fluoxetine during late brain development (adolescence), but not in adulthood, will result in abnormal outgrowth of the 5-HT system. This long-lasting disturbance of the 5-HT system may be visualized using MRI techniques and can…

Effect of a new synbiotic mixture of short chain galacto-oligosaccharides, long chain fructo-oligosaccharides and Bifidobacterium strain on the gut microbiota of caesarean delivered infants.

The study will investigate the effect of a synbiotic test product compared to a control product on the composition and metabolic activity of the gut microbiota of C-section delivered infants.

Assessment of Perinatal Outcome by uSe of Tocolysis in Early Labour: Nifedipine versus placebo in the treatment of preterm premature rupture of membranes.

The aim of the study is to assess whether in women with early PPROM tocolytics improve perinatal outcome.

The Most Effective Treatment Strategy for Diabetic Macular Edema.

Combined (repeated) laser photocoagulation prolongs time to failure compared to anti-VEGF monotherapy.

PACE Plus trial

Low back pain is common and associated with a considerable burden to patients and society. There is uncertainty regarding the relative benefit of Paracetamol and Diclofenac and regarding the additional effect of pain medication compared with advice…

Dyspepsia - Amitriptyline.

N/A

Active plus: implementation and evaluation of two tailored physical activity interventions among the over-fifties.

1. It is hypothesized that participation in the Active plus program contributes to an increase in physical activity behaviour among older adults; 2. Additionally receiving physical and social environmental information results in an extra increase…

The effect of intrathecal methylprednisolone on features of central sensitization in patients with Chronic Complex Regional Pain Syndrome Type 1.

Intrathecal methylprednisolone reduce the features of central sensitization in patients with complex regional pain syndrome type 1 having symptoms longer than 6 months and shorter than 6 years.

Melatonin for children with idiopathic chronic sleep onset insomnia, with or without attention deficit hyperkinesia disorder - A dosefinding trial.
A randomised placebo-controlled double-blind parallel group trial.

Chronic sleep disorders are associated with dysfunctioning during the day. Circadian rhythm disorders are a frequently occurring cause of chronic sleep disorders. The time at which the endogenous melatonin production starts to rise plays a key-role…

Dexamethason for the treatment of exacerbations in multiple sclerosis.

In this double-blind randomized controlled trial, we would like to show that a five-day treatment course with 16mg/day oral dexamethason is effective in inducing recovery from an exacerbation of MS.

Exploration of implicit biases in adults who are current cocaine users

1. A decrease in cocaine use over a three month period in participants who receive AAT training as opposed to VPT training. 2. A change in symptoms involving craving, the urge to use, withdrawals well as stated readiness to change in participants…

Comparison of melatonin, temazepam and placebo for the treatment of sleep problems in hospitalized older patients.

Acutely hospitalized older patients frequently suffer from inadequate sleep. Insufficient sleep can lead to patient distress and delayed recovery from acute illness or a surgical procedure. Currently, no evidence-based treatments exist for sleeping…

STOP PAIN

The primary objective of the study ”STOP PAIN” is to compare the effect on migraine attack frequency of transcatheter device closure of atrial shunting with a non-closure group in migraine patients suffering severe migraine with aura.

An exploratory study to evaluate the effect of a new study product on early programming in healthy infants.

The investigational formula will be equivalent to the control formula with regard to the postprandial blood lipid parameters.

Delirium treatment at the surgical ward (DELTa S)
Treatment of delirium: rivastigmine or haloperidol as primary treatment for delirium in elderly patients with a fractured hip.
A randomized placebo-controlled study.

Rivastigmine is as effective in the treatment of delirium as Haloperidol.

Irritable Bowel Syndrome - Budesonide.

N/A