75 resultaten
To evaluate the safety and tolerability of AP30663 in healthy males at doses up to 12mg/kg
Our hypothesis is that the efficacy of FMT in patients with active UC can be increased by: 1. Pretreatment with budesonide in patients with active UC, which may reduce inflammation prior to infusion of the donor feces solution. This reduced…
Onderzoeken of drie weken lang CBD spanningsklachten kan verminderen bij hersentumorpatiënten in de stabiele fase kan verminderen, en zo kwaliteit van leven kan verbeteren. Depressieve klachten, slaap/vermoeidheid en algehele kwaliteit van leven…
Sacrificing the chorda tympani causes less taste disfunction than stretching or damaging the chorda tympani nerve.
We expect to find that e-liquids with nicotine salts taste milder and are easier to inhale than e-liquids with free-base nicotine. More specifically, we hypothesize that e-liquids with nicotine salts, in comparison to free-base e-liquids: 1. are…
We hypothesize that PHA-022121 will be more effective in both the treatment and prophylaxis of acute angioedema attacks in patients with acquired C1-inhibitor deficiency when compared to placebo.
We expect that the access-related intervention rate and medical costs will be reduced by 40% when correction of vascular access stenosis is triggered by clinically apparent access dysfunction rather than by asymptomatic flow reduction detected by…
In patients with ANOCA, identification of specific endotypes of vascular dysfunction with intracoronary testing, followed by pharmacological and nonpharmacological interventions aligned to the identified endotype, leads to better control of angina…
Based on previous studies, we will expect that ambroxol improves neurological manifestations in patients with GD3.
Part 1 Single Ascending Dose (SAD) - To evaluate the safety and tolerability of a single oral dose of prodrug, ABX-002, in healthy adult subjects Part 2 Multiple Ascending Dose (MAD) -To evaluate the safety and tolerability of once daily oral…
By dosing Ampligen every other day intranasally, it is believed that SARS-CoV-2 can be inhibited at the point of entry, and thus will be much less likely to progress to a pulmonary infection, or moderate COVID-19 disease.
To reduce fatigue symptoms with the use of a bovine lactoferrin supplement in patients suffering from Long COVID.
To investigate the safety, tolerability and pharmacokinetics after multiple daily doses of YTX-7739
We hypothesize that treatment with Tapentadol will reduce the development of chronic postoperative pain by enhancing or maintaining CPM responses and possibly reducing central sensitization. We hypothesize that a 4-week treatment with Tapentadol…
The course of resting energy expenditure (REE), measured by indirect calorimetry changes based on standard versus high enteral protein feeding in the ICU.
The aim of this study is to prospectively assess the efficacy of LDN as induction therapy in CD.
Trend analyses Of Patient-Specific respiratory Physiologal INteractions for weaning decision support
Difficult to wean patients have a mismatch between optimal mechanical ventilation settings lung mechanics and respiratory muscle dynamics
The primary objective is to investigate the effectiveness of a personalized 2-year multidomain lifestyle intervention on cognitive performance in older adults at risk of cognitive decline.
The test product supports normal physical growth in healthy term infants
Let µT denote the mean value of the composite IBS-SSS score under treatment with the active / GOS and µP denote the mean value of the composite IBS-SSS score under placebo, then the primary two-sided hypothesis to be tested is: • H0: µT - µP = 0 (i.…