339 resultaten
Epidural analgesia is superior to placebo in reducing post-operative pain.
Daily supplementation of 3.5g RAR-CLA will slow down cognitive decline as compared to placebo
Does a Attention Control Training in patients in the experimental group with a PTSD prior to the TAU lead to a better outcome than in patients in the control group with a PTSD who have received a sham (fake) training prior to the TAU ? This is also…
We hypothesize that, compared with standard management, NoL-guided anesthesia will lead to reduced postoperative pain scores, and during anesthesia to increased hemodynamic stability.
Overall: when kidney function deteriorates, regulation of the potassium balance in response to potassium loading switches from renal to non-renal mechanisms. 1. Serum potassium in CKD is mainly influenced by alterations in the internal potassium…
adjusting the length of the biliopancreatic limb in MGB based on total small bowel length will lead to a BMI more within normal range while having less deficiencies of vitamins and minerals and less bowel movements and/or complaints compared to a…
We hypothesize that the treatment efficacy of FMT in UC can be augmented by anaerobic stool collection, appropriate donor selection based on their microbiota profile and by enhancing the engraftment by dual route administration. Furthermore, we…
Patients diagnosed with vasospastic angina (VSA) are at increased risk for cardiovascular events. VSA is characterized by endothelial dysfunction and abnormal vasodilatory reserve. Endothelin (ET)-1 is a potent vasoconstrictor peptide produced by…
We hypothesize that 24 weeks of oral magnesium supplementation in patients with chronic kidney disease can improve vascular stiffness, through inhibiting calcification propensity and inflammation. In addition, we test the hypothesis that phosphate-…
This is a Phase I study (not a hypothesis-driven).
- EDP1066 in capsules induces a systemic immunomodulatory effect; - EDP1066 in powder formulation induces a systemic immunomodulatory effect.
Based on previous clinical trials among pregnant women with PCOS-related disorders (e.g. in women with obesity) we expect daily intake of myo-inositol, as a safe nutritional intervention during pregnancy, will result in a 35% reduction in the…
Null hypothesis: placebo is non-inferior to continuous intravenous infusion with buscopan in terms of amount of escape medication used in patients admitted for renal colic.
When administering tranexamic acid during induction of the procedure, there will be less usage of hemostatic clips. Also, postoperatively, patients will have less decrease in hemoglobin value and lesser reinterventions because of hemorrhage will be…
Sound/salient support of treatment recommendations with argumentations will enhance parental recall/agreement/acceptance of these recommendations and enhance their perceptions of the pediatrician/neonatologist as a credible and patient centered…
We hypothesis that a switching strategy based on adalimumab concentration is superior to usual care switching in rheumatoid arthritis patients failing adalimumab.
Proof of concept: to study the effect of tianeptine on opioid-induced respiratory depression in healthy volunteers.
We expect to find increased insulin and decreased glucose in the patient conditioned group in comparison to the patient control group after the placebo administration during the evocation day when controlling for baseline insulin and glucose levels…
Citalopram will reduce chest pain in patients with achalasia.
Semi-annual treatment with zoledronic acid reduces both pain and progression of structural damage in knee osteoarthritis patients with MRI-observed bone marrow lesions