25 resultaten
A single subanesthetic dose of intranasal ketamine is able to diminisch acute suicidal ideation and behaviour, regardless of the underlying diagnosis.
We hypothesize that induction of trained immunity through BCG vaccination may improve host defence mechanisms of patients throughout the perioperative period.
4 weeks of consumption of an infant formula containing milk fat reduces calcium soap formation compared to the reference formula.
Biperiden deteriorate the cognition that biperiden will be used for a challenge model.
Intradermal IMO-2125 treatment can result in a loco-regional anti-tumor immune response and SLN tumor clearance and a longer recurrence-free and overall survival in patients with cT3-4N0M0 melanoma.
In this study we will validate nerve excitability threshold tracking, a measurement technique for neuronal excitability. The placebo-controlled mexiletine and lacosamide administration should inform us about the sensitivity of threshold tracking to…
RTX 1*1000 mg compared to a placebo controlled group leads to a higher proportion of patients in glucocorticoid remission at week 21 in newly diagnosed PMR patients fulfilling the Chuang-criteria
the present study investigates whether Circadian adjusted LED-based (biodynamic) lighting improve cognitive functions, circadian rhytm, behavioral problems (apathy and agitation), Quality of life and mood (depression) in patiënts with moderate- to…
Crohn’s disease (CD) is a chronic inflammatory bowel disorder (IBD) with a major impact on quality of life. Mucosal healing is an important treatment outcome to prevent long term complications of the disease. Regulatory M2 type macrophages play a…
We hypothesize that probiotics with vitamin K2 producing properties can improve vitamin K status.
Ghrelin administration in comatose patients after cardiac arrest is safe, causes no serious adverse events relatable to ghrelin use and it improves functional recovery in these patients.
Leflunomide is able to reduce the relapses, the glucocorticoid use and the adverse events associated with glucocorticoid s use in PMR patients.
We expect that treatment with azelastine/fluticasone propionate will decrease exercise tolerance limitation and will improve quality of life.
Our hypothesis is that preservation of the pectoral fascia may lead to a decreased seroma formation when compared to fascia removal, and has a beneficial effect on breast reconstructive surgery.
Compared to placebo treatment with low dose amitriptyline or mirtazapine during 16 weeks will improve subjective insomnia in insomnia disorder patients in general practice.
The present study explores the dose-response relationship in LSD-induced subjective and cognitive effects using small doses of LSD (5, 10, and 20 µg) compared to placebo. The study hypothesis is that higher doses of LSD will be associated with…
Het doel van het onderzoek of om de werkzaamheid van risankizumab te vergelijken met placebo voor de behandeling van signalen en symptomen van PsA in proefpersonen met onvoldoende respons op of intolerantie voor tenminste een behandeling met een…
In deze studie willen we de werkzaamheid van een 14-daagse interventie met monomere en oligomere flavanolen van Vitis vinifera-zaden en Pinus pinaster-schors (MOF-VVPB), die de werkzame componenten zijn in Masquelières® Frans pijnboomschorsextract…
Het primaire doel van het onderzoek is om het effect van acetaminophen op de hartslag vertraging geassocieerd met de pijn van sociale afwijzing te onderzoeken.
Primaire doel:Onderzoek wat het verschil is distentie van ONSD tijdens endotracheale intubatie versus endotracheale intubatie met lidocaine 1,5 mg/kg IVSecondaire doel:De effect size onderzoeken van het gebruik van lidocaine 1,5 mg/kg IV bij…