3747 resultaten
We hypothesize that MTX can be quantified in semen and that it is associated with measures of semen quality and DNA fragmentation
The effectiveness of an indicated indicated depression and anxiety prevention program ('Een Sprong Vooruit') will be tested in a Dutch sample of adolescents (aged 11-15) with high familial risk. It is expected that the adolescents who…
Information-processing: 1. Changes in measures of severity of OCD are explained (partially) by changes in measures of meta-cognitions (explicit and/or implicit); 2. Changes in measures of meta-cognitions (explicit and implicit) precede changes in…
The overall aim of this RCT is to examine whether an individual music intervention can improve the challenging behavior, quality of life, emotional wellbeing and EF of adults with a mild to moderate ID.
Radiofrequency ablation (RFA) will lead to permanent and complete eradication of Barrett's epithelium. This will prevent development of high grade intraepithelial neoplasia (HGIN) or early carcinoma and may eliminate the need for endoscopic…
H0= Postprandial muscle protein synthesis rates do not differ between the 2 intervention groups (P>0.05) H1= Postprandial muscle protein synthesis rates differ between the 2 intervention groups (P<0.05)
Sunitinib, when given in a high-dose, intermittent schedule, may exhibit improved efficacy with an acceptable toxicity profile.
Changing the context in which individuals make lifestyle choices has a sustained impact on the dietary intake and cardiometabolic health.
We expect an increased bone mineral density in the calcar region compared to the other ROI’s. Furthermore, we expect early detection of decreased mineral density of the femoral head in patients developing osteonecrosis of the femoral head.
The hypothesis to be tested is that arm B is tolerable and that the outcome in arm B is better than in arm A.
We hypothesize that providing feedback to hospitals will reduce practice variation
Objectives Primary: To examine the effects of regular glucose lowering treatment on inflammatory markers in type 2 Diabetes Mellitus Secondary: To identify markers/fingerprints that predict the response of a patient to glucose lowering therapy in…
Een predictor vinden in de vorm van ferritine bij diagnose/leeftijd bij diagnose die het aantal aderlatingen per jaar in onderhoudsbehandeling van hemochromatose patienten kan voorspellen
The hypothesis to be tested is that arm B is tolerable and that the outcome in arm B is better than in arm A.
6MP treatment in pediatric ALL patients can be improved by developing a pediatric oral drinking solution of 6MP, assessing its bioequivalence, and -when successful- introducing the new formulation nationwide.
The rate of unintended events and avoidable harm for elderly hip fracture patients can be reduced by the introduction of three integrated interventions directed at the structure of the handover process, the role of the patient in the care process…
1. ICVAD removal, followed by six months of silicone gel sheet use, will result in a scar width within the normal range, and normal scar structure, and thus will be superior to two months of silicone gel sheets and no gel sheets; 2. A smaller and/…
Objective of the study is to assess the effects of home automation on client satisfaction with services, functioning, fulfillment of needs for care, quality of life, and service contacts.
Obtain transient temperature data of the skin, core and wound surface during orthopedic back surgery in order to validate the numerical model of Severens for this type of surgery.
Mechanical bowel preparation (MBP) is common practice in elective colorectal surgery. In recent literature the value of MBP is subject of discussion. This non-inferiority, randomized study evaluates the value of MBP before colorectal surgery.