29008 resultaten
Because of the high cardiovascular risk profile and functional disabilities of obese long-standing type 2 diabetes patients, therapeutic exercise programs have hardly been evaluated in this subpopulation. The current research proposal aims to…
Training medical specialists in consultation skills focused on MUPS patients improves the specialistic care for these patients in terms of illness worries, course of symptoms and daily functioning and reduces the medical costs for this patient group…
The primary objectives of this project are: - Identify neural correlates and behavioural measures that underlie cognitive processes that perpetuate CFS symptoms - Identify neural mechanisms of change that mediate successful CBT.
Powerspiral enteroscopy provides an effective endoscopic procedure. Total small-bowel enteroscopy can be achieved, in one or two sessions, even in the presence of altered gastro-intestinal anatomy. It provides a great reduction of the enteroscopy…
Addition of liposomal daunorubicin (DaunoXome®) to FLAG in the first reinduction course will result in improved treatment response with acceptable toxicity and without increased cardiotoxicity.
Patients treated with chemotherapy are at higher risk of influenza infection and mortality and morbidity are higher compared to healthy adults. Vaccination against the influenza virus can prevent these complications. Although vaccination in oncology…
Effectiveness of Moving Stories, a game-based school program aimed at depression literacy and stigma
Our first hypothesis is that adolescents who’ve participated in the Moving Stories program will have better mental health literacy and fewer stigmas regarding depression than adolescents who have not participated, both at posttest and at three- and…
Botulinum toxin type A injection of the prostate causes relaxation and cellular apoptosis and by this way will relieve lower urinary tract symptoms in patients with benign prostatic hyperplasia.
The fetus is protected from maternal immune responses through various mechanisms such as lack of expression of classical HLA class I and class II molecules, inhibitory T cell, costimulatory molecules, NK cells, complement regulatory proteins by…
This study will explore the feasibility of post-transplant panobinostat combined with decitabine after reduced intensity conditioning (RIC) alloHSCT in patients with (very) poor-risk AMLor RAEB with IPSS >= 1.5 (AML/RAEB). While recent…
Informed consent procedures and information provision differs between different transplantation centers and transplantation professionals in The Netherlands. Donor knowledge and satisfaction may be influenced by the manner of information provision…
1. To assess the safety and tolerability of different doses of a single IV injection of OTL-038 2. To assess the efficacy of ascending doses of a single IV injection of OTL-038 in detecting ovarian, renal cell or endometrial cancer during surgery by…
We hypothesize that tACS can entrain oscillations in individuals with Classic Galactosemia and relevant frequencies such that they result in improvements of their motor and language performance
Cognitive behaviour therapy and Self-examination therapy are both more effective in reducing depressive complaints than a waiting list control group.
Antidepressant medication does not add any effect to usual consultations by general practitioners in patients with minor and mild-major depression.
Scar defect may give complications on long term. Study is to investigate if the defect is detectable with ultrasound.
Performance of the Aeonose™ as a diagnostic tool to detect lung cancer: an external validation study
Primary Objective: To investigate the diagnostic performance of the Aeonose™ to distinguish breath of subjects suspected for lung cancer who are truly diagnosed with lung cancer from subjects suspected for lung cancer in which this diagnosis is…
No hypothesis due to the explorative character of the study
A peptide representing the first eleven residues of hLF (hLF1-11) was shown to be effective in killing a variety of bacteria in vivo. The objective is to develop hLF1-11 as an effective and safe antibacterial and antifungal for the treatment of…
1- Their is a difference in decline of inhalation technique in children between different devices. 2-The decline in inhalation technique is greater in the home situation compared with the live check in front of a health care professional.