188 resultaten
Primary aim: 1. To investigate whether differences exist in the mitochondrial energy generating capacity of skeletal muscle of statin users with SAMS compared to statin users without SAMS and controls (non-statin users). Secondary aims: 2A. To…
In line with a previous pilot study we hypothesize that 3MDR will significantly decrease PTSD symptom severity in treatment resistant veterans with chronic PTSD in comparison with treatment as usual.
- Smokers are implicitly biased with regard to the pros/cons of smoking (more attention and/or approach tendencies with regard to the pros) - These biases can be retrained using implicit pictorial trainings based on the Visual Probe Task and the…
The RAINBOW study: Rheumatoid Arthritis ImplemeNtation of Biological dose Optimization in real World
We hypothesize that a multifaceted implementation strategy can stimulate the use of tight control and bDMARD dose optimization in clinical practice, measured by decreased bDMARD use and non-inferiority on disease activity at 18 months.
We hypothesize that group medical appointments will enhance adherence to treatment and self-efficacy in patients with sickle cell disease, as well as increase quality of life, and satisfaction with the treating physician and nurse. When performing…
Health outcomes for people at risk of or suffering from non-communicable lung diseases in low-resource settings will be improved by developing capacity for implementation of evidence-based interventions for prevention, diagnosis and treatment in…
To evaluate whether a dietary advice of green vegetables, beef and whole dairy products during six months including standard supportive care can decrease the TSH-level compared to standard supportive care alone in children aged 1-18 years with…
We hypothesize that by using different imaging techniques, we can give a good characterization of the bone marrow microenvironment in advanced-stage myelofibrosis, before and during treatment with ruxolitinib.
With implementation of the AWR we expect a reduction in the total amount of radiographs requested, without missing any clinical relevant fractures. We also expect a reduction in overall waiting times at the ED and a total amount of cost savings…
Fatigue affects central nervous system function and, in the setting of the medical profession, could influence specialist performance, patient care and safety. ln contrast to other industries, for example the aviation industry, there are no "…
H1: the exercise intervention is effective in reducing (work-related) fatigue H2: the exercise intervention is effective in improving (work-related) self-efficacy, sleep quality, work ability, cognitive functioning, and aerobic fitness.
Casein ingested within a normal milk matrix results in a more rapid digestion and amino acid absorption, resulting in greater amino acid availability and post-prandial muscle protein accretion as compared to the ingestion of isolated casein (…
The addition of fluorescence imaging to the standard radio-guided procedure improves intraoperative sentinel node detection.
We hypothesize this difference is due to differences in the mechanisms by which the individuals can withstand and/or adapt to the stress conditions applied in the clinical model and that these mechanisms are of key importance in our ability to…
Our primary outcome is to change knowledge, attitude and managing skills of prison staff. We hypothesis that the elearning module will contribute to improve knowledge, attitude and skills
A proportion of patients with juvenile idiopathic arthritis with minimal disease activity can remain in a state of minimal disease activity with a lower dose of etanercept than the standard dose or even without etanercept.
About 10-15% of the population suffers from chronic insomnia. Structurally poor sleep can have unpleasant consequences for people's health and quality of life. Therefore, proper treatments are of great importance. Fortunately, Cognitive…
To investigate in an unselected memory clinic sample, the clinical value of 18F]FBB PET in terms of 1. change in diagnosis; 2. change in level of confidence of diagnosis; 3. impact on patient healthcare management.
Prosody, both linguistic and emotional, is essential in the acquisition and usage of language and socio-emotional development, but it proves difficult for CI users because of their relative inability to hear spectral and, to a lesser degree, dynamic…
We expect maternal hyperoxygenation in the presence of fetal distress during labor to reduce abnormalities in the fetal heart rate tracing and to reduce the need for assisted birth or a emergency caesarean section without severe maternal or fetal…