213 resultaten
Obesity is a growing world wide problem. In The Netherlands, about 10% of all men and women have a BMI of 30 kg/m2 or more. Obesity is a chronic, uncurable metabolic disorder, which is characterised by excessive fatstorage at unfavorable places.…
Kidney transplantation is the only treatment offering long-term benefit to patients with chronic kidney failure. Urological complications after kidney transplantation, such as urinary leakage and ureteral strictures, are associated with significant…
To evaluate the cost-effectiveness of therapies for male subfertility.
Patient education on extended anticoagulation pros and cons: a journey app in venous thromboembolism
Our hypothesis is that patients whom receive targeted information about VTE and (extended) anticoagulation treatment with the 'patient journey app' on a daily basis in the week preceding their hospital visit will be more satisfied with the…
We hypothesize that depletion of carnitine occurs during infusion of oxaliplatin, due to increased renal loss. This secondary carnitine deficiency may contribute to the development of CIPN.
We hypothesise that the diet over time has become healthier and more sustainable. Our current study was set up to (1) identify the differences in food consumption and nutritional quality over the course of 20 years in the Netherlands using the…
It is hypothesised that compared to waiting list control condition, participants in the intervention improve their diet and physical activity on the short (6 months after baseline) and long-term (12 months after baseline; when the participant…
Current standard treatments for symptomatic benign thyroid nodules (SBTN) are surgery or radioactive iodine. However, these interventions pose a risk to an otherwise healthy person. Therefore, minimally invasive alternatives have been explored.…
The CPCHILD-18+ is sufficiently tested for its psycometric characteristics to be used in clinical practice and research
What is the influence of protective gear on the performance of basic life support (BLS) by KNRM lifeboat crewmembers during a manikin simulation training
Since bleeding risk is high in the elderly we hypothesize that clopidogrel is superior to ticagrelor and prasugrel in terms of causing lesser bleeding events and being non inferior in net clinical benefit in patients above 75 years and CRUSADE…
Supplementation with omega-3 LCPUFA from krill oil in healthy adolescents will result in: - improvement of the omega-3 index - improved cognitive performance - improved mental well-being - better academic achievement
Impairment of immune-complex-induced neutrophil activation caused by PDE4 inhibition, making it a potential target for the treatment of pemphigoid diseases.
Primary hypothesis is that MRDTI will demonstrate acceptable sensitivity and specificity for the diagnosis of acute SVT and the differentiation between acute and chronic SVT.
Information on the dynamics and shape of the device and how these change over time will improve our understanding about the fixation and/or sealing of the device, which may help in stent selection and in designing stent grafts that are more durable.
The hypothesis addressed in this project is that serum calcification propensity is a predictor of coronary artery calcification progression.
The hypothesis states that the time tom complete an emergency airway with Cricath device is significant faster than with Quicktrach device, which will be studied on porcine cadaver models. In the second outcome, the hypothesis states that there is…
Child maltreatment is a major social problem with many adverse consequences. A substantial number of maltreated children is not identified by health care professionals. To improve identification of maltreated children in hospitals, a new hospital-…
The treatment with ciNPT results in a superior healing when compared to the standard treatment (no ciNPT). The rationale behind the secondary outcome is that this treatment leads to improvement of scar quality in comparison to the standard treatment…
Fatigue is expected to be the most prevalent symptom in patients with ILD (IPF and sarcoidosis), next to dyspnoea. Frequency of moderate to severe fatigue in patients with ILD is unknown. In addition, possible correlates of fatigue, including age,…