216 resultaten
Otosclerosis is an isolated ear disorder which can cause hearing and balance impairment. The cause of these symptoms is a disturbed bone metabolism confined to the area of the otic pit, the embryologic predecessor of the inner ear. Most patients…
To investigate whether the clinical outcome is similar after the implantation of the Resolute Integrity stent versus the Promus Element stent (non-inferiority test).
To study the effect of the interaction of cyclooxygenase-2 (COX-2) inhibition (started preoperatively and continued 5 days into the postoperative period) and extended local anaesthetic blockade via paravertebral block on postoperative central…
Non-inferiority (defined as < 12.5% increase) of pooled buffy coat-derived PR platelet concentrates (PR-plasma-PCs) compared to plasma (plasma-PCs) in terms of clinical efficacy determined by WHO grade ≥ 2 bleeding complications.
In line with results from recent pharmacological studies, it is expected that: 1. Inhibiting the cholinergic system by Inversine (Mecamylamine Hydrochloride) results in an impairment of disengagement, but will not affect bias; 2. Inhibiting the…
The null hypothesis of the primary outcome measure is that there will be no significant differences in DASH scores 6 months after surgery between patients who underwent plate fixation or intramedullary fixation with a TEN. The alternate hypothesis…
The primary objective is to demonstrate the non-inferiority of bevacizumab to ranibizumab in the treatment of patients with subfoveal CNV secondary to AMD as determined by the change in best-corrected visual acuity in the study eye from baseline to…
Suppression of SWS, without changing total sleep time, may affect total energy expenditure (TEE), activity induced energy expenditure (AEE), non-exercise activity thermogenesis (NEAT), endocrinological parameters and energy intake.
1. Cooling to 34, 34.5 or 35°C by means of a surface cooling device, started within 4.5 hours after the onset of acute ischaemic stroke and maintained for 24 hours in awake patients on a stroke unit is safe; 2. In awake patients with ischaemic…
Is docetaxel weekly as effective and less toxic than the same dose given 3-weekly.
After receiving PST, stroke patients will have a more effective coping style followed by a better quality of life.
It is expected that the new pre-thickened sip feed is as safe as and well-tolerated as standard sip feed thickened with a commercially available thickener.
The investigational anti-reflux formula will be equivalent to the currently marketed control anti-reflux formula with regard to intestinal tolerance during eight weeks in infants with regurgitation.
The healing of donor site wounds after split-skin grafting can be promoted by the use of one of five specific wound dressing materials as compared in this trial.
1. The effect of cognitive behavioral therapy in internettherapy and face-to-face therapy is larger then without therapy on women with a sexual dysfuntion; 2. The impact of Internet therapy is just as large as the impact of treatment-as-usual (face-…
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Failing in the functionality of patients, who underwent a cervical laminectomy, isn't relate to kyphosis of the cervical spine.
Dietary management of nutrient deficiencies with the medical food under study has a positive effect on cognitive performance in patients with prodromal Alzheimer's Disease.
ICG alone without being absorbed to albumin can be used for near-infrared fluorescence SLNB in breast cancer patients.
Activation of SIRT1 (silent information regulator transcript) results in inhibition of inflammation in humans.