71 resultaten
We hypothesize that the underlying mechanisms of the varying response in multiple parameters within an individual can be attributed to variability in the causal path between drug administration, drug tissue distribution, and tissue receptor…
Dental caries lesions (with ICDAS Codes 3 and 4) can be treated by sealing, offering a less invasive and less costly treatment option with the same results as preparation and restoration of the carious lesions.
The new interdisciplinary protocol will attract attention to these cases of hand injuries and patients will get a chance of a better coordinated treatment at the early rehabilitation phase. To restore early function of the hand proper instructions…
The hypothesis is that all procedures look different per therapist and parent collaboration and all experiences are different. Nevertheless, there possibly will be similarities in experiences and wishes for the future.
Our null hypothesis is that there are no differences in tibiofemoral joint kinematics after ACL reconstruction with LET and the tibiofemoral joint kinematics after ACL reconstruction without LET. Our alternative hypothesis is that ACL reconstruction…
The aims of the study are: To investigate the short-term effectiveness of antecedent and consequent behavioral parent training techniques for parents of children (four to twelve years old) with attention-deficit/hyperactivity disorder (ADHD) on…
The aim of this study is to show whether TDM leads to a lower proportion of patients with drug levels below the predefined TDM targets after 12 weeks
With implementation of the AWR and APWR by the ED triage nurse we expect a reduction in the total number of radiographs requested, without missing any clinical relevant fractures. We also expect a reduction in overall waiting times at the ED and…
KNLTB TennisReady leads to less injuries then current warm up practice of tennisplayers.
Providing vascular surgical patients and vascular surgeons with decision support tools will improve the level of shared decision-making during consultation, increase disease-specific knowledge and quality of life and decrease decisional conflict.
In the Netherlands, 90% of the patients with gout are managed by general practitioners but most research has been done in secondary care. In primary care there are questions on the clinical relevance of long-term uric acid lowering treatment of gout…
to assess the detection rate and accuracy of 18 F-FDHT PET/CT and compare to current standard restaging modalities.
Patients undergoing superior capsule reconstructions (SCR) for superior shoulder instability will experience less pain (decrease of at least 2 points) and improved function.
A decline of intra-tumoral concentrations over time could be the first sign of the development of drug resistance by the tumor. In this exploratory study we will investigate the relationship between plasma and intra-tumoral paclitaxel concentrations…
The aim of this study is to develop and validate an age-specific checklist that can help clinicians to identify elderly patients with personality disorders in need of highly specialized mental health care.
The effects of a video game targeting inhibitory control in a social context will be tested in a Dutch sample of adolescent- and young adult smokers (between the ages of 16 and 26). It is expected that the adolescents and young adults who receive…