48 resultaten
The present study aimed to improve the performance of the A-DIVA scale by identifying predictors other than those included in the original scale. A modified A-DIVA II scale will be created which is applicable in the total hospitalized population to…
To investigate the impact of an open label non-mandatory switching strategy from Enbrel to Benepali on drug survival, effectiveness and safety in a controlled cohort study of RA, PsA and SpA patients in daily practice.
Vitamin D plays an integral role in calcium and phosphorus homeostasis. A low vitamin D status can occur as a result of reduced synthesis due to lack of sun exposure, decreased intake or absorption, increased hepatic catabolism, or decreased…
Sunitinib, when given in a high-dose, intermittent schedule, may exhibit improved efficacy in patients with recurrent GBM with an acceptable toxicity profile, compared to lomustine.
Implementation of Syncope Algorithms (SAs) in the Netherlands will increase diagnostic yield, avoid unnecessary admissions and improve quality of life (QoL) by offering timely diagnosis & treatment
We hypothesize that, asymptomatic patients with severe aortic stenosis, receiving an aortic valve replacement have a better quality of life compared to patients without aortic valve replacement.
A. COMET as an additional transdiagnostic intervention focusing specifically on low self-esteem increases the effectiveness of mentalization based treatment in patients diagnosed with borderline personality disorder. B. This increased effectiveness…
The pharmacokinetics of a therapeutic dose of gemcitabine can be adequatly predicted from the pharmacokinetics of a microdose
- A standardized approach by a multidisciplinary experteam will evactuate a reduction of the use of restraints in care for people with intellectual disabilities
PD-L1 is up to now the only marker that has been validated for the selection of patients treated for non-small cell lung cancer who might benefit from the treatment with PD-1/PD-L1 inhibitors. Thus far, PD-L1 status is assessed with histology, being…
Screening of esophageal cancer can be improved by the optical detection of field cancerization
What is the effect of the systemic antibiotic therapy on the number and diversity of specific bacterial groups in fecal samples of pediatric patients with cancer?
To evaluate the effects of a versatile web-based health game on cognition and compliance in Parkinson’s disease with mild cognitive impairment.
The use of motivational counselling and inclusion of a written health plan in an occupational health examination will improve personal work resources and work ability at 12 months follow-up
Children in the intervention condition will consume (a) more water and (b) less sugar sweetened beverages after the intervention compared to the control condition.
Reveal common mechanisms of compulsivity in OCD and GD and disorder specific characteristics of aspects that have been related to compulsivity: confidence in relation with preference for risky and ambiguous behavior, and (negative) outcome…
During the cooling by a cold cap, the scalp is cooled to 4oC for a long period of time (30 minutes prior to start and up to 45 minutes after the infusion of paclitaxel). This could be of influence on the body temperature. Pharmacokinetics and…
Treatment of a subcapital metacarpal fifth fracture with a compression bandage gives the same functional outcome a treatment with paris plaster
To assess in a randomized comparison the effect of Ibrutinib added to 10-day decitabine treatment on the cumulative CR/CRi rate after 3 cycles. To assess the safety and tolerability of Ibrutinib added to 10-day decitabine treatment for AML (…