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Our hypothesis is that the satiating capacity of protein is partly regulated via the savoury signal of foods. We therefore expect that the savoury diet is more satiating than the sweet diet and the control diet, resulting in a decreased intake after…
NGAL is an early predictive biomarker for acute kidney injury in a heterogeneous adult ICU population.
This study is a phase I trial, testing the safety and toxicity of allogeneic NK cell infusions with an escalating dose of ex vivo expanded NK cells following immunosuppressive conditioning therapy in elderly patients with AML.
It is expected that the CFS patient gets more insight in his or her physical activity pattern, intentions develops to change the behaviour, and really changes the behaviour resulting in a reduction of the CFS complaints.
In the first 6 months Liraglutide affects weight more than CBT, but CBT provides weight maintenance after 12 months.
Time to recurrence of sustained VT (longer that 30 seconds or with hemodynamic instability) or VF with or without documented ICD therapy (shock or ATP) for VT of VF will be longer in patients randomized to substrate based ablation than in patients…
Increased cardiac sympathetic activity is highly prevalent among patienst with chronic heart failure. The increased cardiac sympathetic activity as assessed with 123I-metaiodobenzylguanidine (MIBG) is a usefull tool to discriminate responders (i.e.…
Artificial dynamic lightening can positively influence the sleep/wake cycle and reduce the disturbance of the circadian rhythm due to hospitalization.
Immuune suppression therapy (azathioprine or 6-Mercaptopurine) maintenance therapy is as effective as infliximab maintenance therapy after remission induction with combined infliximab/immune suppression therapy for at least 6 months.
Necessity: A study on chronic pain in persons with Down syndrome is clinical relevant for 5 reasons: 1. The neuropathology of Down syndrome without and with dementia affects pain-related gray and white matter, which may alter pain experience; 2. The…
Compared to usual care, a new perioperative care program will improved recovery and accelerated resumption of (work)activities. Resumption of work contributes significantly to QOL and will prevent disability due to general and mental health problems…
To test if an intraoperative NIRF camera system can detect a NIRF optical contrast agent for SLN in patients with palpable breast cancer.
The aim of this study is to provide evidence based dosing guidelines for vincristine in combination with azoles. Therefore we will study the pharmacokinetics of vincristine with and without concomitant azole therapy in pediatric patients with acute…
It is safe to withhold intravenous broad-spectrum antibiotics in low-risk pediatric cancer patients and to shorten antibiotic treatment in a subgroup of medium-risk pediatric cancer patients presenting with febrile neutropenia.
Our hypothesis is that reverse arthroplasty has a better functional outcome and patient satisfaction than hemi-arthoplasty in patients with a three or four part proximal humerus fracture.