184 resultaten
Tumour cell disruption by radiation generates a surplus of neo-antigens that enhances the effect of immunotherapy in solid malignancies as well as malignant lymphomas. The hypothesis is that the combination of immune checkpoint inhibitors and…
We hypothesize that rectal NSAID prophylaxis use will have significantly risen in comparison to the 2013 survey. We hypothesize biliary endoscopists will show a significantly better risk factor recognition than general gastroenterologists. We…
1. Personalised tools and technologies help to stimulate an increased compliance to a healthy lifestyle in people with overweight and/or obesity and who are cardio-metabolically compromised. Increased compliance may (eventually) lead to a more…
We hypothesize that the ingestion of quark will increase post-prandial muscle protein synthesis at rest in both young and older men. In addition, we hypothesize that exercise will augment the post-prandial muscle protein synthetic response to quark…
We expect that planned visits at the outpatient clinic are unnecessary due to low percentage of treatment changes. Furthermore, we expect that treatment changes will appear at unplanned visits.
The level of AGEs can predict response to intravitreal anti-VEGF therapy in DME
A higher percentage of patients with MRD levels <0.1% (MRD negativity) after up to 2 courses of induction chemotherapy plus quizartinib, as measured in the bone marrow using MFCM before start of consolidation therapy, compared to a historical…
Pre-operative comprehensive digital Cardiac Counseling (prehabilitation) will reduce the cumalative incidence of MACE at 1 year postoperatively in patients operated for a cardiovascular procedure.
DOACs are non-inferior to LMWH with regard to the risk of ICH in patients with brain cancer requiring anticoagulation.
The null hypothesis will be that the prevalence of bruxism and TMD, in PD patients will be higher than in their peers without PD. Also, we hypothesized that factors as medication use, disease severity, psychosocial factors and lifestyle factors are…
Based on literature we assume a 20% day 30 mortality of patients admitted to the hospital ward with COVID-19. We aim to lower this day 30 mortality to 10%.
The hypothesis of this trial is that reusable catheters are as safe and efficient as single use catheters and will be cost-effective.
The amount of skin tension and the direction of highest skin tension is influenced by posture changes and the location of the body.
The one-year graft survival of a second kidney transplant will be inferior to the one-year graft survival of a first kidney transplant.
The implementation of an activity tracker in usual care leads to an increased level of physical activity and recovery of physical functioning after discharge
The higher hardness/protein density of protein gel would delay gastric emptying and protein hydrolysis in humans; MRI technique can used to monitor gastric digestion (in this case: protein hydrolysis) in humans.
Main hypothesis The BENEFIT intervention will significantly increase the number of CVD patients that can maintain the healthy lifestyle behavior most relevant to them for at least one year, compared to care-as-usual. Secondary hypothesis The BENEFIT…
Knowledge generated by this study can contribute to the development of an approach to perinatal health inequities that can be implemented in all municipalities in the Netherlands, regardless of their size, location, and previous experience with…
The hypothesis is that the MicroShunt will lead to a similar IOP lowering compared to trabeculectomy, and will be a cost-effective alternative for trabeculectomy.
To study the predictive value of illness perceptions, fear of cancer recurrence, medication beliefs and quality of life on adherence to endocrine treatment at 12 months. To study adherence to endocrine therapy at 3 and 6 months. To compare cross-…