7296 resultaten
To investigate whether the addition of preoperative radiochemotherapy to the standard treatment, consisting of explorative laparotomy, pancreaticoduodenectomy if possible, followed by adjuvant chemotherapy, improves the overall survival (analyzed by…
Atherosclerosis of the intracranial arteries has shown to be correlated with a high recurrent stroke risk. Our primary hypothesis is that intracranial vessel wall atheromas are an important underlying cause of obstruction of arteries of the anterior…
Establishing that microTEE can view the same required anatomical features as TEE and ICE for their respective purposes.
The goal of the present study is to investigate whether the blockade of NA-transmission by beta-antagonist propranolol reduces the common EMDR effects (reduced vividness/emotionality of emotional memories) in order to find out if NA-release (evoked…
In the post-ICU hospitalization, the nutritional intake of post-ICU patients is below targets (based on predicted requirements)
The primary hypothesis is that local antibiotics are a safe treatment option in the prevention and treatment of fracture-related infections, achieving higher local concentrations without the potential adverse events associated with systemic…
1. The first hypothesis is that treatment of panic disorders with or without agoraphobia with EMDR as well as with CBT will lead to symptom reduction. This symptom reduction is expected to be larger in the EMDR treatment group than in the CBT…
It is unclear if DOACs are superior or inferior compared to VKAs in CTEPH/CTED patients regarding (peri-procedural) bleeding and long-term (thrombotic) complications.
We hypothesize that the active strategy leads to a better functional outcome than the conservative strategy three months after acute ischemic stroke, in patients with elevated pre-treatmen blood pressure otherwise eligible for intravenous…
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Primary Objective: Our primary objective is to compare the midterm clinical and radiographic results (6 to 8 years) of CWO versus OWO with a locked plate fixation in the management of patients with medial knee OA and a varus leg alignment with a…
Pelvic floor related symptom and Quality of Life questionnaires (IIQ-7, UDI-6, IIEF-5, PISQ-12, PFIQ-7, PFDI-20, FISI, FIQL) in Dutch are valid instruments, which can be used reliably in daily practice and clinical research.
1. does pseudophakia influence intra ocular pressure (IOP) lowering effect of SLT? 2. the effect of SLT relies on an inflammatory reaction. Anti-inflammatory therapy is often used immediately following SLT, does this influence the IOP lowering…
Video endoscopic cordotomy technique is safe, provides effective pain control and has very few and manageable complications
To demonstrate proof of principle for the elimination of malaria from Rusinga Island using the nation-wide adopted strategy of LLINs and case management augmented with mass trapping of mosquito vectors.
Endoscopic dilatation of pancreatic duct strictures with biodegradable self expandable stents will decrease the need for further therapeutic interventions (endoscopic or surgical), as compared to dilatation with plastic stents.
To quantify the amount of local anaesthetic in blood and tissue fluid in the Bellovac ABT system and in the blood circulation of the patient. The primary objective is to quantify the cumulative ropivacaine level when the blood should be retransfused…
Online treatment based on imagery rescripting is effective in the treatment of nightmares
The rationale of the study is based on three arguments: 1. Aggressive thyroid carcinomas are characterized by an abundant local inflammatory tumor microenvironment and associated with systemic inflammation 2. Inflammation, and especially…
We hypothesize that before clinical manifestation of NEC, urine I-FABP, serum GLP1/2, faecal Calprotectin, faecal TLR4 (on shedded enterocytes) and faecal bile acids can be used as predictive markers for NEC. We also hypothesize that Near Infrared…