203 resultaten
The study aims to assess the efficacy (in terms of growth response over the years of treatment, including final height) and safety of a treatment regimen consisting of: 1. Authentic biosynthetic growth hormone (GH) in a dosage of 4 IU/m2/day between…
An unsupervised proprioceptive balance board training programme that is applied after the usual care of individual athletes who have sustained an acute sports-related lateral ankle ligament injury is effective for the prevention of ankle sprain…
Locoregional anesthesia does not work as well in patients with the Ehlers-Danlos syndrome as in people who do not have this syndrome.
A self-management programme guided by doctors and a specialist asthma nurse through information and communication technology will improve asthma related quality of life in a cost-effective way.
Optimum timing of surgery for macula off rhegmatogenous retinal detachment can be determined in more detail by taking both duration and height of macular detachment into account.
Systematic screening for type 2 diabetes in high-risk obese subjects, identified from the general population, can significantly reduce the diabetes-related cardiovascular morbidity and mortality by at least 25% compared with not offering a screening…
Implantation of aspheric IOL's results in higher visual performance than spheric IOL's.
Fluoxetine has in animals and cell cultures neuroprotective properties. We test whether fluoxetine is able to reduce progression in patients with multiple sclerosis.
Strategies involving shorter and milder ovarian stimulation protocols and single embryo transfer may allow for more IVF cycles in the same period of time, resulting in similar term live birth rate per treatment period despite a minor reduction in…
The tested intervention (level 5 intervention of Triple P, an intensive individual training for the family of children with behavioural problems) will cause a decrease in behavioural problems in children, dysfunctional parenting styles in parents,…
Maintenance thalidomide delays the time to progression with 50% in patients who do not progress after > 3 cycles of pemetrexed containing chemotherapy.
Cultured mesenchymal stem cells differentiated into osteoblasts and seeded on scaffolds can induce bone formation.
A restrictive fluid regimen is beneficial for postoperative recovey after abdominal surgery, as to hospital stay and postoperative complications.
Type 2 diabetes is cause by progressive beta-cell dysfunction against a background of obesity and insulin resistance in susceptible individuals. Peroxisome proliferator-activated receptor (PPAR) gamma-mediated mechanisms are involved in the…
It is hypothised that a pain consult at the specialized pain clinic in combination with Patient Education Program is more effective in reducing average pain intensity compared to a pain consult alone. A pain consult at the specialized pain clinic is…
The intervention will primarily effect the level of patient control with regard to glycemia, lipid levels and blood pressure. We will expect a substantial decline in the occurrence and severity of complications and mortality and an improved quality…
We hypothesize that the use of Carbon Dioxide (CO2) reduces the incidence of (air) microembolism during aortic arch surgery, and that it also positively influences the gross neurologic and/or the neurocognitive outcome of this kind of surgery.
Prednisone inhibits progression of joint damage in early RA-patients, even when intensive treatment, according to a strict computer-assisted protocol, is applied.
A single subconjunctival Celestone chronodose injection immediately following cataract extraction reduces the incidence op post-op ocular inflammation when compared with conventional post-op eye drops therapy. Post-op administration of eserine does…
Cinacalcet is able to control hypercalciemia due to hyperparathyreoidism after renal transplantation ergo avoiding surgical removal of parathyroidtissue without jeopardizing renal function or eliciting serious adverse events.