748 resultaten
We hypothesized a beneficial effect of IUI in couples with an isolated cervical factor. Furthermore we hypothesized that the post-coital test can identify those couples who would benefit from IUI without ovarian hyperstimulation.
1-2 intramuscular injections with 100 mg dexamethason in persons without arthritis but with elevated serum levels of rheumatoid factor and or anti-CCP will lead to a reduction in antibody concentrations after 6 months and possibly to a lower…
Obinutuzumab can provide clinical benefit in patients with rituximab-refractory follicular lymphoma
Care providers are more likely to adhere to clinical practice guidelines when they receive guideline-based decision support by an electronic system.
In this study, we expect to decrease the number of referrals and repeat smears by immediately referring those women who are positive for hrHPV with mildly abnormal smears for colposcopically-directed biopsies. Thus, for the remaining women with BMD…
An upfront RBCT aiming at low-normal Hb levels will ameliorate anemia-caused tumor hypoxia-related resistance to chemotherapy before the start of chemotherapy and may decrease secondary anemia-induced endogenous release of cytokines like VEGF,…
For the prevention of diabetic foot ulceration, evidence exists to support the use of home-monitoring of foot skin temperature by means of a hand-held infrared skin thermometer. However, the construct validity of skin temperature measurements is…
Pre- and probiotics are able to change the composition of the altered intestinal microbiota that is found in allergic patients, indicating beneficial effects of these nutritional components in the prevention and treatment of allergic diseases. The…
In this project the hypothesis is tested that the community pharmacist-led CATI care programme in patients using cardiovascular medication, will have a beneficial effect on patients’ adherence to cardiovascular medication and improves clinical…
1. Methylphenidate (MPH) increases activation in task relevant areas and task performance 2. Hydrocortisone (HC) increases activation in task relevant areas and task performance 3. MPH + HC increase activation in task relevant areas, but might…
The guided online CBT intervention is expected to show favorable effects and to be cost-effective in comparison to care-as-usual for patients with insomnia in general practice
We expect that depressive adolescents will show a stronger increase in heart rate during, as well as a slower recovery afterwards, when they are left in the game or when they encounter fearful stimuli compared to non-depressive adolescents. Finally…
a one-day-visit systematic assessment in a specialized severe asthma centre contributes to improvement in asthma control, quality of life and health care utilization after 1 year
N/A
The primary goal of the present research proposal is to investigate whether the stimulation of β-adrenergic stress hormone systems by α2-receptor antagonist yohimbine causes the common EMDR effects (i.e., reduced vividness) for emotionally neutral…
Children with cochlear implants (CIs) learn Dutch through the input of their CIs, which offers qualitatively different sensory input than ears. Therefore, these patients are thought to develop auditory processing patterns different from normal-…
Persistent atrial fibrillation is associated with (increased) dissociation between the sub-endocardial and sub-epicardial layers of the atria
It is postulated that the investigational treatment has superior efficacy based on observations of longterm remissions in a number of patients, although this has to be balanced against potentially higher toxicity.