322 resultaten
We hypothesize that propofol combined with ketamine has a optimal physician’s satisfaction, patient’s satisfaction and hemodynamic stability, in comparison with propofol combined with either alfentanil or remifentanil.
Whole Body Vibration (WBV) applied via a chair has positive chronic effects on cognitive function of older people.
Ventilation-associated pneumonia (VAP) is an important complication in intubated mechanically ventilated patients. VAP is associated with a substantial increase in morbidity, mortality, and cost. One of the most relevant causes of VAP is passage of…
1) Implementing TIPP will prevent acute emergency room (ER) visits, rehospitalisations and inappropriate referrals 2) Implementing TIPP improves transitional patient safety culture 3) Although TIPP aims at reducing transitional incidents,…
It is expected that the urinary and serum level of intestinal fatty acid binding protein (I-FABP) and the urinary level of Claudin-3 have prognostic relevance for early identification of patients at risk for intestinal ischemia-related morbidity or…
When this new knee system will facilitate a high knee flexion, this will be depicted in a superior knee function. In addition, a high flexion ability will result in high clinical and functional outcome scores and high patient satisfaction.
Een "systeem biologische aanpak" kan nieuwe diagnostische markers en oorzakelijke immuunprocessen identificeren bij patiënten met artritis psoriatica.
A high protein diet and resistance exercise have a positive effect on fat free mass, fat mass, muscle strength, physical functioning and quality of life compared to regular dietary and exercise advice according to CBO guidelines for treatment of…
Behavioural Activation is effective in reducing acute major and minor depression in elderly.
• CT based Signature™ will result in a comparable percentage of prosthesis that is placed correctly (within guidelines of 3 degrees varus and 3 degrees valgus). • CT-based Signature™ will result in a comparable alignment of the prosthesis as…
1) Tapering of SSRIs with added preventive cognitive therapy (CT) increases the risk of clinically relevant maternal relapse of depression in excess of [absolute] 15% compared to continuation of SSRIs. If rejected, then discontinuation is deemed non…
The overall aim of this study is to study the effectiveness of a PLISSIT-model intervention in men and women with type 2 diabetes in primary care. Primary outcomes include sexual functioning, sexual satisfaction, and quality of life. Secondary…
The central hypothesis is that the mobile programme is more effective than the web-based programme in increasing physical activity (PA). i.e. 1. Both intervention groups will show an increased PA level. 2. Participants of the mobile programme…
This study has 2 primary objectives: 1) To determine the time point of induction of VEGF expression in the tumour tissue of oesophagus carcinomas during chemoradiation. 2) To determine whether the tumour promoting effects of this induction of VEGF…
The primary objective is to estimate the frequency of subjects with at least one apnoeic episode, defined as respiratory rate ≤6, detected using the respiR8® device for up to 6 hours after surgery. Apnoea is defined as 10 seconds of no breathing…
We hypothesize that age-related changes in hepatic and intestinal drug metabolism affect the pharmacokinetics of paracetamol.
- The incidence of PONV will be higher in the group receiving dexamethasone alone - There will be no significant difference in the incidence of PONV between the two groups receiving two anti-emetic drugs - There will be less postoperative agitation…
The use of a decision support system will increase adherence to the ESC guideline for atrial fibrillation in terms of calculation of bleeding and stroke risk, and accurate anti-thrombotic treatment for stroke prevention.
We hypothesize that adaptation or tuning of the population PKPD model of propofol will decrease the residual error between predicted and measured plasma-concentrations during maintenance of anaesthesia. The adapted PKPD models can also be used…