602 resultaten
The hypothesis is that stratification of the referred population by the two referring screening radiologists using a validated design (BI-RADS, screening variant) can lead to a fast track workflow with only imaging tools, which would enable us to…
Wet-wrap treatment with diluted corticosteroids is more effective than wet-wrap treatment with emollients only
Primary research question: Is there a difference in effectiveness and costs of clozapine treatment compared to olanzapine treatment in the reduction of substance use disorders of patients with schizophrenia and related psychotic disorders?…
The primary objective is to investigate to what extent early IVIG treatment in children with newly diagnosed acute ITP reduces the risk of development of chronic disease. Secondary objectives are: 1. To estimate the alteration in the clinical…
Early lipid and extra amino acid administration is safe and effective and leads to improved short- and long-term outcome.
COPCA (Coping and Caring) intervention in infants at high risk for cerebral palsy will result in better functioning than Tradional Paediatric Therapy.
Comparison of progression free survival (PFS) in elderly patients with advanced CRC treated first line by tegafur-uracil plus LV or capecitabine. It is considered that, in this patient population, only differences in the median time to progression…
Walking, an aerobic exercise, has a positive effect on physical fitness, cognition, circadian rythm and mood
The infusion of intrathecal baclofen using higher flow rates results in more extensive intrathecal distribution, hence benefits pharmacodynamic properties of baclofen
Renal function improves when converting stable livertransplant patients from cyclosporin to tacrolimus; it also improves with Bayesian C4 monitoring compared to C0 monitoring on tacrolimus.
Large head metal-on-metal arthroplasties show less bone mass density loss (DEXA)and higher serum metal ion concentrations. We expect equal functional scores, greater range of motion, less dislocations, fewer periprosthetic radiolucencies and…
We hypothesize that expiratory Volatile Organic Compounds analysis by an electronic nose is capable of discriminating between asymptomatic infants and infants with respiratory wheeze.
What is the effectiveness of Diclofenac compared to Paracetamol over a period of two weeks and if necessarily another two weeks (consistent with the Dutch guidelines for general practitioners) in new consulters with knee osteoarthritis in the…
BoneMaster IEen vergelijking te maken in de klinische, botremodelering en radiologische resultaten tussen de conventionele Hydroxyl-Apetite (HA) Taperloc steel vergeleken met Taperloc steel met additionele BoneMaster® coating in patienten met een…
Het primaire doel van dit onderzoek is die vrouwen met borstkanker te identificeren die uitgesproken subjectieve en/ of objectieve cognitieve stoornissen 1 jaar na chemotherapie ervaren en vervolgens de factoren te vinden die bijdragen aan die…
Doelstelling van dit onderzoek is het vergelijken van magnesium(hydr)oxide en macrogol/elektrolyten ten aanzien van preventie van obstipatie en bijwerkingen van deze medicamenten bij patiënten met kanker in de palliatieve fase die starten met…
Primair doel:Het inschatten van het verschil in aanhoudende virale respons (SVR, sustained viral response) waarden tussen T12/PR24 en T12/PR48 behandeling regime in proefpersonen die eRVR behalen.Secundair doel:De veiligheid beoordelen van…
Het primaire doel van deze studie is het analyseren of het gebruik van MECC bij AVR leidt tot minder cerebrale microembolien gemeten d.m.v. bilaterale Trans Craniale Doppler en afname ivan de transfusie van RBC en FFP.Tevens wordt gekeken of er een…