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Our first hypothesis is that both guided and unguided online CBT lead to a decrease in the severity of PCBD, PTSD, and depression symptoms. Our second hypothesis is that people allocated to the guided online CBT group will show a stronger decrease…
We hypothesize that therapeutic drug monitoring of risperidone in children with an autism spectrum disorder and comorbid behavioral problems will reduce metabolic side effect burden, while retaining clinical effectiveness.
I. Test whether psychological and psychophysiological indices of PC are differentially affected by fantasizing vs. mindfulness in remitted MDD patients and HC: Pre-and peri-intervention changes will be examined using within-subject and between-group…
This is a superiority trial testing the hypothesis that analgesic ear drops as added to usual care (oral analgesics with/without antibiotics) provide superior ear pain relief over usual care in children aged 1 to 6 years with a GP-diagnosis of AOM…
The aim of this study is to characterize the proportion and extent of patients who return-to-work and who enter (partial) disability pension in a “labouring class” of patient infected by COVID-19, who were admitted to the hospital for medium- and/or…
We hypothesize, that SCD patients ending with mixed mononuclear chimerism after non-myeloablative HSCT with alemtuzumab/TBI conditioning will preserve their immune response to vaccinations administered prior to the transplantation and will therefore…
The primary research questions are: 1. To what extent does a 4 week ReHab-TOAT regime lead to improvement of arm function in chronic stroke patients with either a severely or moderately affected arm-hand? 2. To what extent is any improvement of arm…
Infants’ growth when consuming hydrolysate-based formula is similar to growth when consuming a control formula with intact protein.
The EMPOWER-GR RCT will test the hypothesis that a combined intervention of RET and protein supplementation with an oral nutritional supplement (ONS) is feasible in sarcopenic geriatric rehabilitation inpatients admitted after a hip fracture and…
The use of DeltaScan for delirium screening reduces length of hospital stay and increase the detection of delirium, in comparison with the Delirium Observation Scale
Implementation of the positive health tool will lower the medical care use and will improve experienced overall health for the patient.
The objective of this study is offloading the peak plantar pressure in Diabetic patients with loss of protective sensation by using the self-adjusting insoles and individually optimized rocker profiles. The secondary objective is to evaluate the…
To generate proof that convalescent antibody-mediated treatment of ICPs, who suffer from COVID-19 disease can protect ICPs from a more severe course of disease.
It is hypothesized that (relapse) clubfoot patients show reduction in participation, lower motor ability and larger deficits in movement patterns during dynamic tasks compared to typically developing children.
Main research questions: 1) Does the photo intervention, compared to having a general conversation, have more positive effect on mood, social interaction and quality of life of people with dementia in nursing homes, personal attitude and empathy of…
The hypothesis of this study is that a proactive strategy keeps the blood pressure at a safe margin and avoids dropping below the minimal acceptable threshold of a MAP of 65 mmHg. This proactive strategy may improve postoperative disability and…
We hypothesize that preoperative initiation (7 days before surgery) and perioperative continuation (until day 2 after surgery) of empagliflozin 10 mg daily (10 days total) will reduce the postoperative concentration of NGAL in plasma on…
Testing trials: 1. We expect to see a main effect of time on number a) of tests completed b) of persons who get tested c) of tests per person 2. We expect to see a main effect of letter condition. Specifically, we expect that the…
We postulate that a set target range of 92%-96% will result in a more stable SpO2 and accompanying reduction of time spent with an SpO2 <91% and similar or less time >96% when compared to a target range of 91%-95%.
The aim of the study is to compare outcome after management of proximal humeral fractures by evaluating outcomes of patient populations in daily clinical practice, where disagreement exists about operative or nonoperative treatment.