557 resultaten
The hypothesis is that STEMI patients who are pre-treated with crushed ticagrelor and paracetamol have a higher level of platelet inhibition after primary PCI than patients pre-treated with crushed ticagrelor who are treated with fentanyl.
The hypothesis is that cummulative doses of 2.5, 5.0 or 7.5 gram methylprednisolone infusions are equally effective in moderately severe Graves' ophthalmopathy, but that the doses differ in the number and severity of side effects.
To compare a surgical procedure (gastrojejunostomy, GJJ) with endoscopical stent placement in patients with malignant gastric outlet obstruction (GOO)
The purpose of the study is to conduct a randomised controlled trial with the onlinecourse 'Voluit Leven' as an intervention to study the: 1. Cost-effectiveness in terms of reduction of psychological symptoms (mood symptoms and disorders…
Nicardipine might decrease adverse maternal and neonatal outcome due to its pharmacokinetics and fewer side-effects.
The hypothesis to be tested is that arm B is tolerable and that the outcome in arm B is better than in arm A.
We hypothesize that providing feedback to hospitals will reduce practice variation
The overall aim of this study is to implement bariatric surgery including the multidisciplinary care pathway around the procedure for unsuccessfully treated adolescents with severe obesity in the Netherlands. Therefore, feasibility, efficacy and…
The hypothesis to be tested is that arm B is tolerable and that the outcome in arm B is better than in arm A.
6MP treatment in pediatric ALL patients can be improved by developing a pediatric oral drinking solution of 6MP, assessing its bioequivalence, and -when successful- introducing the new formulation nationwide.
The rate of unintended events and avoidable harm for elderly hip fracture patients can be reduced by the introduction of three integrated interventions directed at the structure of the handover process, the role of the patient in the care process…
1. ICVAD removal, followed by six months of silicone gel sheet use, will result in a scar width within the normal range, and normal scar structure, and thus will be superior to two months of silicone gel sheets and no gel sheets; 2. A smaller and/…
Given the high prevalence and burden associated with sexual problems and the existence of barriers to seek treatment among gynaecological cancer patients, there is a clear need for a brief, inexpensive and effective psychosexual rehabilitation…
Objective of the study is to assess the effects of home automation on client satisfaction with services, functioning, fulfillment of needs for care, quality of life, and service contacts.
The hypothesis to be tested is that the outcome in arm B is better than in arm A.
The combination of breast surgery, radiotherapy and chemotherapy have a profound effect on the deep myofascial level and in turn, they create a vicious circle of adhesions and lack of mobility and pain in muscles, fasciae and joints around the…
It is hypothesized that the E-health self-management treatment results in lower impact of the disease on daily life, primarily a lower level of distress, in comparison to care as usual. As secondary objectives the effectiveness of the treatment on…
We hypothesize that a treatment algorithm that is based on a simple validated measure of health status (CCQ) improves quality of life (as measured on a separate scale) and other classical COPD outcome measurement parameters such as exacerbation…
A constant Hb concentration will improve the quality of life of patiënts with a chronic need for bloodtransfusions.
Computer-tailored safety information combined with personal counseling results in: 1. Improved parents¡¦ child safety behaviors; 2. Improved satisfaction with different elements of intervention.