348 resultaten
Primary objective: - To evaluate the safety and tolerability of NT-0167 in healthy volunteers Secondary: - To evaluate the pharmacokinetic (PK) profile of NT-0167 in healthy volunteers after the administration of single ascending (SAD) and multiple…
• clonazepam administration has acute beneficial effects compared to placebo on neurocognitive tests. • multiple-doses clonazepam has beneficial effects compared to placebo on behaviour and cognitive function in ARID1B patients as measured by the…
Intake of 30ml Montmorency tart cherry juice twice a day during 4 weeks will reduce MCP-1 mRNA expression in omental adipose tissue.
The main objective of the study is to investigate if positional therapy during sleeping, using the LEFT device, reduces nighttime gastroesophageal reflux symptoms.
The hypothesis is that random assignment to C1-INH in patients with moderate and severe TBI will experience a reduction in ICP directed therapy intensity levels (TIL) compared to random assignment to placebo (difference of 2.2). Secondary, if…
We aim to test the hypothesis that increasing excitability of the cerebellum – through cerebellar tDCS – improves also the non-motor features of cerebellar disorders, and more specifically CCAS, in patients with cerebellar disorders. If we are…
Primary Objectives • To assess the pharmacodynamic effects of prednisolone on the IMQ-induced inflammatory response • To assess safety & tolerability of topical IMQ in combination with prednisolone Secondary Objectives • To explore…
30% improvement is the minimal effect found in previous microneedling studies, based on this studies we expect to find a 7.5 point improvement on the POSAS total score
This is a set-up for a challenge pruritus model. We expect to initiate a local, reversible itch- response
Sacroiliac joint infiltration with bupivacaine 0.25% is superior to placebo in reducing post-operative pain.
This study is exploratory and no formal hypothesis is set.
More physical activity will increase protein synthesis rates of muscle tissue and will decrease protein synthesis rates of prostate tissue and prostate tumor tissue.
Subjects randomized to the probiotics group will have a lower score on the Chalder Fatigue Questionnaire after 12 weeks of treatment compared to the placebo group.
The main objective is to evaluate the efficacy and safety of phenytoin cream in patients with neuropathic pain due to CIAP
We hypothesize that probiotics with vitamin K2 producing properties can improve vitamin K status, which will eventually reduce the risk of coronary calcification.
We hypothesize that GABA could improve glucose tolerance and cardiovascular health after long-term supplementation
Primary Objective To evaluate the safety and tolerability of topical XZ.700 in patients with mild to moderate atopic dermatitis Secondary Objectives To investigate the PD effects of XZ.700 in patients with mild to moderate atopic dermatitis To…
Foods consisting of whole dairy, butter, beef and locally grown seasonal vegetables with a balanced composition of omega 3 and 6 fatty acids and a wide range of essential micronutrients and anti-inflammatory capacities have a protective effect on…
We hypothesize that BCG vaccination may reduce hospital admission and improve the clinical course of symptoms of elderly people during the SARS-CoV-2 outbreak.
2gr of Cefazolin is effective as prophylaxis for surgical site infections following implant removal below the level of the knee.