317 resultaten
In the proposed study we will investigate the effect
Adjuvant therapy of levamisole to prednisolone prevents relapses in children with a first episode of idiopathic nephrotic syndrome.
- Intradialytic protein ingestion increases plasma total amino acid concentrations throughout hemodialysis compared to placebo. - Intradialytic exercise increases amino acid loss into the dialysate in fasted patients and decreases amino acid loss…
PRP injections are efficacious for symptom reduction and functional improvement compared to placebo injections in the treatment of ankle (talocrural) OA.
A single subanesthetic dose of intranasal ketamine is able to diminisch acute suicidal ideation and behaviour, regardless of the underlying diagnosis.
We hypothesize that induction of trained immunity through BCG vaccination may improve host defence mechanisms of patients throughout the perioperative period.
• To determine if buprenorphine action at the MOR receptor can inhibit the respiratory depression response to IV fentanyl injection in healthy subjects and patients with chronic opioid use; • To determine if therapeutic concentrations achieved with…
Biperiden deteriorate the cognition that biperiden will be used for a challenge model.
Intradermal IMO-2125 treatment can result in a loco-regional anti-tumor immune response and SLN tumor clearance and a longer recurrence-free and overall survival in patients with cT3-4N0M0 melanoma.
In this study we will validate nerve excitability threshold tracking, a measurement technique for neuronal excitability. The placebo-controlled mexiletine and lacosamide administration should inform us about the sensitivity of threshold tracking to…
After a runic phase of 2 weeks, we will study whether cotreatment of oral E hallii once daily given for 2 weeks on top of stable metformin dosage improves (postprandial) glycemic control in DM2 subjects compared to once daily glycerol placebo with…
RTX 1*1000 mg compared to a placebo controlled group leads to a higher proportion of patients in glucocorticoid remission at week 21 in newly diagnosed PMR patients fulfilling the Chuang-criteria
To determine the safety and tolerability and to assess the PK and performance of VB5-845D-800CW in healthy volunteers and patients
adults. We hypothesize that test product NL-01, which is an extract from food crops enriched for IMPP-1, a compound that supports innate immune function, increases resistance to acute respiratory tract infections (ARTI) in the winter season
Sodium phenylbutyrate administration in patients with T2D would improve whole body insulin sensitivity.
The primary aim of this project is to further elucidate the (neural) mechanisms of ketamine, which may underlie its (rapid) antidepressant response.
the present study investigates whether Circadian adjusted LED-based (biodynamic) lighting improve cognitive functions, circadian rhytm, behavioral problems (apathy and agitation), Quality of life and mood (depression) in patiënts with moderate- to…
Evaluation of the safety and tolerability of AP3066 in healthy males
It is hypothesized that chicken eggshell membrane is effective in the regeneration of cartilage and/or immunomodulation (oral tolerance), and as such positively affects pain and stiffness in joints commonly affected in arthritis