132 resultaten
Onderzoek naar de werkzaamheid, veiligheid en tolerantie van oraal R129160, 60 mg/dag in volwassen patiënten met chronische idiopathische urticaria (CIU).
We hypothesized that patients treated with Methotrexate (MTX) will have less duration and less severe arthritis, will not or less evolve into RA, will develop less radiographic progression in joint damage, and are more likely to go into remission.
1. The effect of a single oral dose of L-000830982 versus oral placebo and an intravenous infusion of ethanol versus placebo on tremor over a 8-hour period in men and women with essential tremor will be estimated; 2. The sensitivity and specificity…
S(+)-ketamine reduces pain in patients with Complex Regional Pain Syndome type 1 having symptoms shorter than 6 months and longer than 3 years.
1-2 intramuscular injections with 100 mg dexamethason in persons without arthritis but with elevated serum levels of rheumatoid factor and or anti-CCP will lead to a reduction in antibody concentrations after 6 months and possibly to a lower…
Pre- and probiotics are able to change the composition of the altered intestinal microbiota that is found in allergic patients, indicating beneficial effects of these nutritional components in the prevention and treatment of allergic diseases. The…
To determine the cost-effectiveness of CBT compared to care as usual in patients with a recent onzet of schizophrenia, who suffer from persistent and recurrent symptoms of psychosis.
The severity of hazelnut allergy will decrease as an additional effect by birch pollen immunotherapy.
Primary study objectives: 1. To test the reproducibility, in atopic subjects with a clinically stable allergic rhinitis, of: a. SPT; b. Relevant markers of allergic rhinitis and atopy in peripheral blood; 2. To validate the following assays for…
Approximately 1/3 of persons with IGT develops type 2 diabetes mellitus in 5-10 years time. Acarbose is an alpha-glucosidase inhibitor decreasing post-prandial glucose levels, without the risk of hypoglycemia. The prevention of diabetes with…
This is a pharmcological study to examine the ability to reverse respiratory depression from opioids such as morphine and M6G by low dose naloxone.
Combined pneumococcal vaccination with influenza vaccinatoin reduces the occurrence of RTI in children with recurrent RTI.
Probiotics are tolerated well by infants (age 0-3 months) and results in a microbial flora resembling that of breastfed infants.
Rifampicin is an effective chemoprophylactic intervention method to prevent leprosy among close contacts of leprosy patients.
We assume that relaxation of the subscapular muscle will lead to pain reduction and improvement of mobility in stroke patients with shoulder- or armpain and limited range of motion of the shoulder.
Bifosfornates in combination with vitamin D and Calcium is more effective that Vitamin D and Calcium alone for Crohn’s disease related osteopenia.
A large proportion of chronic patients with complex regional pain syndrome type 1 suffer from both neuropathic pain and dystonia. Findings from neurophysiological and intrathecal baclofen studies highlight an impaired inhibitory neurotransmission.…
Ascorbic acid has shown to have a favorable influence on myelination in in vitro studies and in a mouse model for CMT1A. We will study the efficacy and safety of ascorbic acid treatment in young patients with CMT1A.
To study the effects of a pre-operative supplemental enteral feeding with IMPACT® on the systemic inflammatory response to cardiopulmonary bypass and on immunological parameters will be examined.