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In this explorative study we will examine the impact of daily ischemic preconditioning on brachial artery endothelial function (measured as FMD%, before and after IRI) during 7 days in the non-shunt arm and lower limb in patients with end-stage…
Different studies have shown that a hunter-gatherer type diet is effective in improving glucose regulation and lipid profile. I want to investigate if the hypothese that this type of diet also reduces the number of physical and psychological…
RRT activation rate within a hospital or wards within a hospital are likely to be associated with specific factors regarding possible delay in escalation of care for deteriorating patients. This research is focussed on elucidating factors which may…
Patients could be stratified into a high-risk or a low-risk group so surveillance intervals can be tailored and the clinical and economic burden of endoscopic surveillance can be reduced.
There is considerable interlaboratory variation in the grading of dysplasia in duodenal adenomas.
We hypothesize that patients with symptoms of inability to belch have ineffective UES relaxation in response to esophageal distention caused by air.
- Hypothesis#1 efficacy We hypothesize that a quick onset, and a predictable dose-response, good adjustability of analgesia can be achieved with inhaled ketamine. Hypothesis#2 safety Inhalation of nebulized ketamine might lead to a fast onset of…
Perfusion Angiography, in relation with known parameters, describes the ultimate prognostic model in revascularized Critical Limb Ischemia patients.
Primary Objective: The main study parameter is to establish the safety of the use of IXSI in an interventional setting. Safety will be assessed based on the CTCAE methodology. Use of IXSI will be considered safe in the absence of Adverse Device…
We hypothesize that frailty in older individuals might underly low responses to the 23-valent polysaccharide pneumococcal vaccination (PPV23) that will be implemented in the National immunization program in autumn this year for elderly 73-79 years…
Data on these complications vary. Since this is an observational study, we are interested in overall incidence and prevalence. Therefore we do not have a clear hypothesis.
Severe SARS-CoV-2 infection (admitted patients) have significant burden of long-term sequelae: inflammatory response, functional decline, pulmonary fibrosis, lung function abnormalities, cardiac dysfunction and/or psychological sequelae
It is hypothesized that the FitMáx© questionnaire is a valid clinical assessment tool for CRF compared to the gold standard, a cardiopulmonary exercise test. Moreover we believe the FitMáx© to be fairly accurate in the preoperative risk assessment…
Our hypothesis is that high-dose, pulsatile sorafenib may exhibit improved efficacy with an acceptable toxicity profile compared to standard continuous dosing. AUC escalation cohorts are used instead of the conventional dose escalation cohorts,…
Similar or better fixation, migration and functional outcomes compared to other existing techniques
MIA is a good alternative for the CA, with comparable diagnostic performance. It will lead to an increase in clinical autopsy rates, which have significantly decreased over the last decades in both academic and non-academic medical centers.
We hypothesise that the health behaviour of pregnant women is influenced by the measures to prevent the spread of COVID-19. It is not clear however, if it is positively affected (because of having more time, providing online options, creating a…
To determine the feasibility of the measurement protocol of a large prospective longitudinal study to describe the exercise capacity and physical functioning of critical illness survivors up to 5 years after discharge from the ICU.
We hypothesize that rectal NSAID prophylaxis use will have significantly risen in comparison to the 2013 survey. We hypothesize biliary endoscopists will show a significantly better risk factor recognition than general gastroenterologists. We…
The RAINBOW study: Rheumatoid Arthritis ImplemeNtation of Biological dose Optimization in real World
We hypothesize that a multifaceted implementation strategy can stimulate the use of tight control and bDMARD dose optimization in clinical practice, measured by decreased bDMARD use and non-inferiority on disease activity at 18 months.