315 resultaten
Oral 6-thioguanine (6TG) results in a high intrahepatic exposure to 6TG generated metabolites.
There have been several studies that showed a possible positive effect of electrical stimulation on wound healing. One of the working principles is increasing blood flow. This could mean that by giving frequent electrical stimulation on the foot and…
The objective is to assess which Transfusion Triggers are used in Blood-conserving Trials in Lower Limb Arthroplasty and to assess the prevalence of usage of Transfusion Triggers in time.
1. When patients visit their GPs with unexplained complaints it is cost effective to follow a watchful waiting strategy of four weeks before ordering laboratory tests; 2. A systematically developed quality improvement strategy, based on barriers…
Women with POI have low androgen blood levels which leads to less overall sexual satisfaction, less frequent desire and more pain during sex.
For BE patients with visible lesions containing high-grade dysplasia (HGD) or early cancer (EC) upon biopsy, a single session treatment in which the BE is first ablated using radiofrequency ablation (RFA) followed by the endoscopic resection (ER) of…
The purpose of this study is: 1. To evaluate the effect of a high intensity implementation strategy compared to a regular intensity strategy; 2. Identify success factors and obstacles for mplementation of thrombolysis; and 3) to assess the cost-…
Prolactinomas influence angiogenesis.
We hypothesize that the molecular and systemic response to calorie restriction is more explicit in obese compared to normal weight individuals to explain there propensity to grow obese.
Characterization of subjects with non-atopic asthma and phenotyping of the disease by linking clinical, functional and molecular markers will: 1. Give more insight in the underlying pathophysiological mechanisms of non-atopic asthma; 2. Show that…
There is incomplete adherence to the recommendations from the guidelines on caesarean section among Dutch gynaecologists.
1. Omitting complete inguinofemosal lymphadnectomy in patients with negative sentinel nodes is sufficient; 2. Morbidity associated with the sentinel node procedure is limited; 3. Frozen section, immunohistochemistry and multiple sectioning are…
Flumazenil is a substrate of P-glycoprotein at the blood-brain barrier.
N/A
In patients with end-stage heart failure (NYHA class III or IV, LVEF <35%, QRS duration >120 ms, LBBB), the dyssynchrony of the left ventricle is the most important predictor of clinical benefit. The dyssynchrony of the left ventricle…
Participation in a health survey for elderly people (60-75 years) on risk factors for cardiovascular diseases, depression, osteoporosis and falls, followed by a subsequent personalized health advice from a community nurse on lifestyle modification…
With the use of the special rd needle, the yield of oocytes will not be diminished when compared with the use of the routine needle. Moreover the percentage of top quality oocytes wil be the same with the use of both needles.
The aim of this programm is to stimulate people to follow the medical instructions and therefore to optimise the rehabilitation process and the bonehealing. In this project a prototypes was fabricated and will be used in twenty patients with a…
Our hypothesis is, that the extrinsic mechanism in the etiology of SIS is only valid for a subgroup of patients; complaints of SIS can be caused by 1) a pathologic pattern of arm-scapula movements caused by a disrupted balance in muscle forces,…
The Internet 'Self-Examination Therapy' (SET) on anxiety, depression and burn-out wil be effective in reduction of complaints (depression, anxiety, burn-out).