57 resultaten
There are two research questions: 1. Does cognitive behavioural therapy (CBT) in groups lead to a significant decrease of fatigue and functional impairment of CFS patients compared to a waiting list condition? 2. For which patient is group therapy a…
The two tested interventions (Good Behavior Game and parent management training) will cause a decrease in aggression, victimization, disruptive behavior, anxiety and depression in elementary school children.
MPS I patients can be treated with Aldurazyme safely and effectively.
An upfront RBCT aiming at low-normal Hb levels will ameliorate anemia-caused tumor hypoxia-related resistance to chemotherapy before the start of chemotherapy and may decrease secondary anemia-induced endogenous release of cytokines like VEGF,…
Patients with high scores on anxiety and neuroticism will experience a lower Quality of Life after breast conserving therapy compared to modified radical mastectomy.
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Hypothesis: The implementation of microarray diagnostics is feasible in general practice in community hospitals.
About 6% of the population between 3 and 79 years suffers each year of a B.pertussis infection, also pregnant women. These women are a source of infection for their newborn babies.
The usual treatment for warts in Dutch general practice is cryotherapy with liquid nitrogen. More than 50% of all warts are treated with cryotherapy alone and in only 14% salicylic acid is used as mono-therapy. The prestigious Cochrane review…
anatomy sparing 2-incision total hip arthroplasty (THA) has a better functional outcome than conventional THA.
Multivariate Nuclear Magnetic Resonance (NMR) can be used to measure oxidative stress in patients suffering from intermittent claudication.
Serum testosterone levels in men will be related to basic cognitive functions, such as mental processing speed and cognitive control.
5-Aminosalicylates influence the metabolism of thiopurines leading to higher levels of the pharmacological end-metabolite 6-thioguaninenucleotides.
In patients with end-stage heart failure (NYHA class III or IV, LVEF <35%, QRS duration >120 ms, LBBB), the dyssynchrony of the left ventricle is the most important predictor of clinical benefit. The dyssynchrony of the left ventricle…
1. When patients visit their GPs with unexplained complaints it is cost effective to follow a watchful waiting strategy of four weeks before ordering laboratory tests; 2. A systematically developed quality improvement strategy, based on barriers…
1. Omitting complete inguinofemosal lymphadnectomy in patients with negative sentinel nodes is sufficient; 2. Morbidity associated with the sentinel node procedure is limited; 3. Frozen section, immunohistochemistry and multiple sectioning are…
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The Internet 'Self-Examination Therapy' (SET) on anxiety, depression and burn-out wil be effective in reduction of complaints (depression, anxiety, burn-out).
The purpose of this study is: 1. To evaluate the effect of a high intensity implementation strategy compared to a regular intensity strategy; 2. Identify success factors and obstacles for mplementation of thrombolysis; and 3) to assess the cost-…