189 resultaten
The objectives is to clarify what the distribution and interrelation is of relevant clinical microbial, biochemical and immunological parameters of the oral ecosystem in a systemically healthy (non diseased) young adult population. Such biodata…
We hypothesize that the CPA Talking-with-children-intervention will have a beneficial effect on the mental health and quality of life of maltreated children. We expect that children who participate in the CPA investigation (CPA Talking-with-…
Patients with a BMI > 30 kg/m2 in the ICU have a higher incidence of pressure ulcers and wound infections in the ICU compared with patients with a BMI 18-25kg/m2. They develop them sooner during admittance and the severity and time to…
We will develop a bi-daily low-dose metronomic treatment schedule with paclitaxel in a convenient oral formulation and test whether this therapy has significant anti-angiogenic and anti-tumor activity.
Atrial fibrillation (AF) is the most common cardiac arrhythmia with a prevalence of 1-2% in the general population, increasing with age. It is associated with a 5-fold increased risk of stroke if untreated. While anticoagulant agents are effective…
Reproducible test-retest assessment of [18F]FDG PET.
The robotic-assisted technique will allow the ascertainment of ‘Critical View of Safety’ in all anatomical variations.
Uterine cervical cancer is the second most common female malignancy. Therapy monitoring is essential to detect early recurrence. Diffusion-weighted magnetic resonance imaging is an emerging MRI imaging technique which has a potential value for the…
Part A: In clinical practice the use of simplified quantitative methods and procedures can be fully validated against complex quantitative kinetic measures. Part B: Test-retest repetability of different SUV measures, metabolic and anatomic volume…
Our first hypothesis is that in the two exisiting case management models, the persons with dementia will have less behaviour and mood problems than persons receiving usual care and informal caregivers experience better mental health compared to…
Hypothesis is that there are big differences in ROM between age categories in healthy persons.
The aim of this study is to investigate how an increase in the implementation of tailored expectant management in Dutch fertility care can be best achieved. In this study we want to determine the effects of a multifaceted implementation strategy…
The prevalence of multiresistant organisms (MRO) like MRSA and ESBL are higher in farmers and livestock builds an important reservoir. In farmers occur other types than in the hospital.
A disruption of the biological clock is presumed in hemodialysis patients since they frequently suffer from sleep problems and lack a nocturnal melatonin surge, which is a reasonable readout for disturbed clock performance. The origin of these…
The analysis of exhaled breath by electronic nose measurements can discriminate between subgroups of children with different levels of asthma control.
The AKITA® JET nebulizer is a new inhalation device with breath controlled inhalation. It regulates inspiration flow as well as inhalation volume, taking into account therapeutic requirements and the patient's individual condition. Doing so, it…
We hypothesize that MBM may have significant advantages over the ER-cap technique, especially in countries where endoscopic expertise is limited. The aim of this study was to assess the feasibility, safety and effectiveness of the MBM technique for…
There will be no issues with regards to tolerance in relation to the switch from the current to the new high energy, nutrient enriched infant formula.
Relative to controls, remitted depressed patients have: 1. Increased negative attentional biases; 2. Decreased functional and effective connectivity between emotion-regulation networks; 3. Increased activations of the cognitive control system when…