2772 resultaten
Patients could be stratified into a high-risk or a low-risk group so surveillance intervals can be tailored and the clinical and economic burden of endoscopic surveillance can be reduced.
AIM: Establish the clinical value of sentinel node biopsy in patients with multiple breast tumors. Investigate if an intratumoral tracer injection in the additional tumors results in visualization of extra sentinel nodes/extra lymphatic drainage…
Before we start with our research on assessing the diagnostic value of TMS-EEG in epilepsy, we perform this pilot study to investigate a number of methodological aspects. To be able to develop a sound protocol these aspects need to be explored in…
Based on the results obtained in our previous study (Ruiter, Kolk, Rietveld, Dijkstra & Lotgering, 2011), we hypothesise that: - The experimental changes to the scenarios and new quantitative scoring procedure of the Amsterdam-Nijmegen…
To determine whether a second dose of IVIg in GBS patients with a poor prognosis improves functional outcome after 4 weeks. Secondary outcomes include functional outcome after 8, 12 and 26 weeks, duration of mechanical ventilation, length of…
There is considerable interlaboratory variation in the grading of dysplasia in duodenal adenomas.
1. A higher resting and funtional PFM activity is observed in more distal areas from the introitus of the vagina. 2. A higher resting and funtional PFM activity is observed on the anterior wall of the vagina
The age-specific seroprevalence of a cross-section of the Dutch population for the vaccinations used in the Dutch National Immunisation Programme.
We hypothesize that patients with symptoms of inability to belch have ineffective UES relaxation in response to esophageal distention caused by air.
- Hypothesis#1 efficacy We hypothesize that a quick onset, and a predictable dose-response, good adjustability of analgesia can be achieved with inhaled ketamine. Hypothesis#2 safety Inhalation of nebulized ketamine might lead to a fast onset of…
It is expected that the dynamic version of the Wisconsin Card Sorting Test (dWCST) is a valid measure of cognitive learning potential in terms of psychometric properties and construct validity. In terms of feasibility it is anticipated that the…
We hypothesize that lower renal region or cerebral NIRS values are correlated with a higher incidence of postoperative AKI in this study population
Primary Objective: The main study parameter is to establish the safety of the use of IXSI in an interventional setting. Safety will be assessed based on the CTCAE methodology. Use of IXSI will be considered safe in the absence of Adverse Device…
To test the hypothesis that observing the data and waveforms displayed on an respiratory function monitor during the provision of positive pressure ventilation to preterm infants at birth will increase the proportion of tidal volumes within a…
The main hypothesis is that use of Oncokompas will be superior to care as usual to reduce caregiver burden and to improve self-efficacy and quality of life, and it is expected that Oncokompas will improve quality-adjusted life years (QALYs) at…
We hypothesize that frailty in older individuals might underly low responses to the 23-valent polysaccharide pneumococcal vaccination (PPV23) that will be implemented in the National immunization program in autumn this year for elderly 73-79 years…
Data on these complications vary. Since this is an observational study, we are interested in overall incidence and prevalence. Therefore we do not have a clear hypothesis.
Cultured mesenchymal stem cells differentiated into osteoblasts and seeded on scaffolds can induce bone formation.
We hypothesise that there will be no (substantial) differences between both scans for all relevant parameters (e.g. fat mass, lean mass, and bone mineral density) when the same subjects are measured on the same day, under the same conditions.
The two tested interventions (Good Behavior Game and parent management training) will cause a decrease in aggression, victimization, disruptive behavior, anxiety and depression in elementary school children.