36 resultaten
The main clinical challenge remains to identify patients who may benefit from aggressive local treatment (stereotactic radiotherapy, SBRT) of soft tissue oligometastases: for which patients can systemic treatment be postponed? Patients who are…
SARS-CoV-2 is present in the cerebrospinal fluid of COVID-19 patients with acute respiratory failure
To evaluate the effects of thoracic epidural anaesthesia (TEA) with general anaesthesia on mean systemic filling pressures, arterial- and venous resistance and cardiac output. To assess the hemodynamic effects of vasopressors and fluid loading under…
As EGFR plays a role in pathogenesis of both pulmonary arterial hypertension and systemic sclerosis, EGFR inhibition will lead to beneficial effects in disease course.
The aim of this study is to assess the predictive value of the HowRwe questionnaire in relation to the EUROPEP questionnaire by analyzing scores acquired in Dutch GP practices. We expect that high HowRwe scores are associated with an positive…
The primary hypothesis of this study is that Opsys will improve mild incontinence based on urine loss per 24 h measured by 24 h pad weight test (PWT). Primary Objective The primary objective of this study is to test the effectiveness of Opsys in a…
The gastric balloons are expected to remain in the stomach for approximately four weeks, after which they burst and are fecally excreted. It is further hypothesised that intragastric balloons can provide a surrogate stomach fill, inducing an…
Multi-centre open label clinical trial.
Simvastatin (an HMG-CoA reductase inhibitor) induces apoptosis in vitro and sensitizes the myeloma cell to chemotherapy. This is the first clinical trial to test if in vivo there is the same sensitization in relapse or refractory multiple myeloma.
1. Welke rokers hebben baat bij welke transmurale “stoppen-met- roken- interventiestrategie”?; 2. Wat zijn de effecten van de verschillende “stoppen-met- roken- interventiestrategieën”?
The aim of the study is to gather information regarding COVID-19 infections during pregnancy. Up to now, little is known about COVID-19 during pregnancy.
We hypothesize that chemotherapy-induced changes in exhaled metabolites in lung cancer can be detected by changes in VOC profiles (smell-prints) measured by the eNose.
Dietary fibres and vinegar has been suggested to lower the postprandial blood glucose and insulin response and this may be explained by a delayed gastric emptying.
There are three main hypotheses: 1.visceral adiposity is associated with increased risk of recurrence and with decreased survival, 2.indicators of low muscle quality (low muscle mass, low muscle attenuation and increased inter-muscular fat areas)…
Rivastigmine is as effective in the treatment of delirium as Haloperidol.
1) Surveillance of patients with a urine test, followed by cystoscopy only when the urine test is positive, results in detection of a the same or a higher number of recurrences and is cost-effective and 2) urine diagnostics contribute to earlier…
We hypothesize that an electronic nose can discriminate the VOC pattern in exhaled breath between patients with non small cell lung cancer (NSCLC) and breast cancer.
1. Which factors influence electronic cigarette use?
The size of intrinsic foot muscles is associated with gait biomechanics and balance in older adults