188 resultaten
We hypothesize that it is possible to culture circulating tumor cells obtained by leukapheresis into organoids.
We hypothesize a priori that the Dutch NAT: PD-HF will be a feasible and acceptable tool to identify palliative care needs in patients with CHF and will initiate appropriate management.
We expect that the Dutch language versions of the AOFAS Ankle-Hindfoot and the AOFAS Midfoot score will have adequate measurement properties (e.g. reliability and validity).
intravenous immunoglobulins will induce a fast and effective response in patients with newly diagnosed idiopathic inflammatory myopathies. Also, the treatment will be generally safe. Furthermore, this pilot study will show feasibility with respect…
The main outcome is the identification of clinical, biochemical, and genetic factors associated with resilience to cognitive decline in extreme elderly subjects. At baseline we will test the association between cognitive resilience and amyloid…
In TMD patients with concomitant headache, t is hypothesized that treatment of the TMD complaints will have a positive effect on the headache as well. The effect size is expected to depend on the type of headache, with the strongest effect for…
Because of the increasing incidence of work-related musculoskeletal disorders of the upper extremities, the UEWD questionnaire was developed as a riskassessment that takes less time and less expenses then an observation. The aim of this study is to…
To evaluate the validity, reproducibility and scale functioning of the Dutch clinician-based Constant-Murley (CM) score and of a Dutch patient-derived Constant-Murley score in patients with shoulder arthroplasty. To define the smallest detectable…
We expect that treating patients with the IlluminOss® System will result in excellent recovery
The purpose of this study is to evaluate toxicity and feasibility of MRI-guided focal salvage high-dose-rate brachytherapy (HDR-BT) in patients with locally recurrent prostate cancer. In comparison with whole-gland salvage techniques, focal…
The purpose of this study is: 1. To investigate the effectiveness of teacher training in Classroom Pivotal Response Teaching (CPRT) on teacher-created opportunities 2. To investigate the effectiveness of CPRT on children's communication…
Our hypothesis is that MRKH patients are exposed to high concentrations AMH in utero, coming from their male co-twin (possible vanished twin). This AMH-exchange is possible because of intrauterine blood exchange between two fetuses. This blood…
The beneficial effect of cold acclimation on insulin sensitivity is reproducible and the effect wil sustain for a longer period of time. Besides insulin sensitivity, cold acclimation also has beneficial effects on cardiovascular risk factors in type…
The main objective of this study is to determine the rate people convey information through their hand. The secondary objective is to assess the mental workload of the subjects through a questionnaire. Moreover, as we already have pilot data from…
Screening of esophageal cancer can be improved by the optical detection of field cancerization
Het krijgen van meer inzicht in de mechanische eigenschappen van zacht weefsel onder hoog risico voor diepe drukwonden met US en MRI Elastografie.
Het onderzoeken van de longembolie-gerelateerde kwaliteit van leven op lange termijn en het meten van de cumulatieve incidentie van PTS patienten met acute DVT, behandeld met heparine plus edoxaban vergeleken met patienten die behandeld zijn met…
Het eerste doel is ontwikkelen van informatiematerialen in samenwerking met patiënten en professionals die het afbouwen van antidepressiva kunnen ondersteunen: patientfolder, decision aid en afbouwprotocol.Het tweede doel is de effectiviteit…
Het doel van deze pilot studie is meer inzicht te verkrijgen in de neurale correlaten van tanden klemmen (gedurende waken) en tmd pijn bij bruxers en non-bruxers of meer specifiek:1.Wat is de mate van hersenactiviteit gedurende tandklemmen bij (waak…