40 resultaten
• There is no difference in number of bonding failures between the direct and indirect bracket bonding methods • Patients favour indirect bracket bonding over direct bracket bonding • Brackets bonded with the indirect bracket bonding will have less…
The study will address the feasibility of the shared decision-making (SDM) intervention by (1) analysing the acceptability of the intervention by users (i.e. professionals and patients); (2) assessing the level of implementation; (3) testing…
Subjects with a divergent PGx phenotype experience more side effects and/or reduced drug efficacy compared to those with a PGx phenotype in normal range.
et eerste doel van dit onderzoek om geschikte én haalbare meetinstrumenten te vinden voor kinderen met AS. Deze kunnen worden gebruikt voor (medicijn)onderzoek. Een tweede doel van dit onderzoek is 'deep phenotyping': om nauwkeurige en…
Het vaststellen van de PK / PD-relatie van prednisolon met betrekking tot toxiciteit als klinische uitkomst bij pediatrische patiënten met auto-immuunziekten of auto-inflammatoire aandoeningen.
Virtual reality hypnose is net zo effectief als de gebruikelijke medische hypnose bij het verminderen van pijn en angst tijdens prikgerelateerde procedures bij kinderen in een ziekenhuis.
Tones vs. neutral self-voice (EEG experiment 1 in Session 3; Pinheiro et al., 2018): a) no effect of HP on N100 suppression for self- and externally generated tones as we would expect alterations in sensory feedback only with regards to one’s own…
Vitamin C deficiency may play a role in the symptoms of patients with chronic kidney failure and eventually renal replacement therapy
We hypothezise that patients with a primary tumor expressing ER and lacking HER2 but with CTCs expressing HER2 have a worse response on hormonal therapy.
As changes in gutmicrobiota composition could play a role in the development of autoimmune diseases including hypothyroidism, we will investigate whether repetitive fecal transplantation from either allogenic (healthy) or autologous (own) fecal…
The quality of life of adult patients with NMD can be enhanced by providing capability care in comparison to usual care.
To determine the musculoskeletal safety of standard prophylactic treatment with ciprofloxacin and co-administered glucocorticoids in pediatric patients with acute lymphoblastic leukemia (ALL).
De experimentele behandeling (game-ondersteunde TPM-training) zal bijdragen aan een effectievere generalisering van compensatiestrategieën in ongetrainde taken vergeleken met de actieve controlegroep (CogniPlus training).
Vaststellen of het in de praktijk haalbaar is om patiënten met COVID-19 (of andere luchtweginfectie) middels een nieuwe werkwijze in de thuissituatie optimaal te behandelen en te monitoren.
There might be discrepancies in number and type of Cancer Predisposition Syndrome diagnoses between the genotype first and the phenotype first approach.
Critical illness, along with the lack of zeitgebers on the PICU environment, and iatrogenic influences like medication and procedures, results in disturbed circadian rhythms in critically ill children, which is important for their recovery.
Het onderzoeken van de relatie tussen farmacokinetiek en farmacodynamiek van prednisolon als zowel profylaxe als therapie bij graft-versus-host ziekte in kinderen na hematopoetische celtransplantatie.
Mainstreaming of germline genetic tests in regular healthcare is feasible for healthcare professionals and acceptable for both patients and healthcare professionals
To determine the frequency of the most common causes of hospitalizations abroad, repatriation or death of Dutch business and leisure travellers in recent years to identify risk groups for serious health problems.
We hypothesize (based on literature) that the incidence of chronic pain in The Netherlands is around 15-20% in patients presenting to the emergency department with (acute) pain related complaints. We have no further hypothesis, because of the…